Dorsal striatal dopamine, food preference and health perception in humans.
To date, few studies have explored the neurochemical mechanisms supporting individual differences in food preference in humans. Here we investigate how dorsal striatal dopamine, as measured by the positron emission tomography (PET) tracer [(18)F]fluorometatyrosine (FMT), correlates with food-related...
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doaj-75b729e32e224c7bae5a9b57ba69ffac2020-11-25T00:23:38ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0195e9631910.1371/journal.pone.0096319Dorsal striatal dopamine, food preference and health perception in humans.Deanna L WallaceEsther AartsLinh C DangStephanie M GreerWilliam J JagustMark D'EspositoTo date, few studies have explored the neurochemical mechanisms supporting individual differences in food preference in humans. Here we investigate how dorsal striatal dopamine, as measured by the positron emission tomography (PET) tracer [(18)F]fluorometatyrosine (FMT), correlates with food-related decision-making, as well as body mass index (BMI) in 16 healthy-weight to moderately obese individuals. We find that lower PET FMT dopamine synthesis binding potential correlates with higher BMI, greater preference for perceived "healthy" foods, but also greater healthiness ratings for food items. These findings further substantiate the role of dorsal striatal dopamine in food-related behaviors and shed light on the complexity of individual differences in food preference.http://europepmc.org/articles/PMC4012945?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Deanna L Wallace Esther Aarts Linh C Dang Stephanie M Greer William J Jagust Mark D'Esposito |
spellingShingle |
Deanna L Wallace Esther Aarts Linh C Dang Stephanie M Greer William J Jagust Mark D'Esposito Dorsal striatal dopamine, food preference and health perception in humans. PLoS ONE |
author_facet |
Deanna L Wallace Esther Aarts Linh C Dang Stephanie M Greer William J Jagust Mark D'Esposito |
author_sort |
Deanna L Wallace |
title |
Dorsal striatal dopamine, food preference and health perception in humans. |
title_short |
Dorsal striatal dopamine, food preference and health perception in humans. |
title_full |
Dorsal striatal dopamine, food preference and health perception in humans. |
title_fullStr |
Dorsal striatal dopamine, food preference and health perception in humans. |
title_full_unstemmed |
Dorsal striatal dopamine, food preference and health perception in humans. |
title_sort |
dorsal striatal dopamine, food preference and health perception in humans. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2014-01-01 |
description |
To date, few studies have explored the neurochemical mechanisms supporting individual differences in food preference in humans. Here we investigate how dorsal striatal dopamine, as measured by the positron emission tomography (PET) tracer [(18)F]fluorometatyrosine (FMT), correlates with food-related decision-making, as well as body mass index (BMI) in 16 healthy-weight to moderately obese individuals. We find that lower PET FMT dopamine synthesis binding potential correlates with higher BMI, greater preference for perceived "healthy" foods, but also greater healthiness ratings for food items. These findings further substantiate the role of dorsal striatal dopamine in food-related behaviors and shed light on the complexity of individual differences in food preference. |
url |
http://europepmc.org/articles/PMC4012945?pdf=render |
work_keys_str_mv |
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