Vitamin D status, bone mineral density and mental health in young Australian women: the Safe-D study
<em>Background</em>. Vitamin D deficiency has been associated with both poor bone health and mental ill-health. More recently, a number of studies have found individuals with depressive symptoms tend to have reduced bone mineral density. To explore the interrelationships between vitamin...
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doaj-75ba3d6252ee455a8b352cc842514cfb2020-11-24T21:22:21ZengPAGEPress PublicationsJournal of Public Health Research2279-90282279-90362015-11-014310.4081/jphr.2015.594129Vitamin D status, bone mineral density and mental health in young Australian women: the Safe-D studyEmma T. Callegari0Nicola Reavley1Suzanne M. Garland2Alexandra Gorelik3John D. Wark4on behalf of the Safe-D study team5Department of Medicine, Royal Melbourne Hospital, University of Melbourne, ParkvilleMelbourne School of Population and Global Health, University of Melbourne, ParkvilleMurdoch Children’s Research Institute, Royal Children’s Hospital, Parkville; Royal Women’s Hospital, Parkville; The University of Melbourne, ParkvilleMelbourne EpiCentre, Royal Melbourne Hospital, University of Melbourne, ParkvilleDepartment of Medicine, Royal Melbourne Hospital, University of Melbourne, Parkville; Bone and Mineral Medicine, Royal Melbourne Hospital, ParkvilleMelbourne<em>Background</em>. Vitamin D deficiency has been associated with both poor bone health and mental ill-health. More recently, a number of studies have found individuals with depressive symptoms tend to have reduced bone mineral density. To explore the interrelationships between vitamin D status, bone mineral density and mental-ill health we are assessing a range of clinical, behavioural and lifestyle factors in young women (Part A of the Safe-D study). <br /><em>Design and methods.</em> Part A of the Safe-D study is a cross-sectional study aiming to recruit 468 young females aged 16-25 years living in Victoria, Australia, through Facebook advertising. Participants are required to complete an extensive, online questionnaire, wear an ultra-violet dosimeter for 14 consecutive days and attend a study site visit. Outcome measures include areal bone mineral measures at the lumbar spine, total hip and whole body, as well as soft tissue composition using dual energy x-ray absorptiometry. Trabecular and cortical volumetric bone density at the tibia is measured using peripheral quantitative computed tomography. Other tests include serum 25-hydroxyvitamin D, serum biochemistry and a range of health markers. Details of mood disorder/s and depressive and anxiety symptoms are obtained by self-report. Cutaneous melanin density is measured by spectrophotometry. <br /><em>Expected impact.</em> The findings of this cross-sectional study will have implications for health promotion in young women and for clinical care of those with vitamin D deficiency and/or mental ill-health. Optimising both vitamin D status and mental health may protect against poor bone health and fractures in later life.http://www.jphres.org/index.php/jphres/article/view/594Vitamin Dbone mineral densityosteoporosisdepressiondual energy x-ray absorptiometry |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Emma T. Callegari Nicola Reavley Suzanne M. Garland Alexandra Gorelik John D. Wark on behalf of the Safe-D study team |
spellingShingle |
Emma T. Callegari Nicola Reavley Suzanne M. Garland Alexandra Gorelik John D. Wark on behalf of the Safe-D study team Vitamin D status, bone mineral density and mental health in young Australian women: the Safe-D study Journal of Public Health Research Vitamin D bone mineral density osteoporosis depression dual energy x-ray absorptiometry |
author_facet |
Emma T. Callegari Nicola Reavley Suzanne M. Garland Alexandra Gorelik John D. Wark on behalf of the Safe-D study team |
author_sort |
Emma T. Callegari |
title |
Vitamin D status, bone mineral density and mental health in young Australian women: the Safe-D study |
title_short |
Vitamin D status, bone mineral density and mental health in young Australian women: the Safe-D study |
title_full |
Vitamin D status, bone mineral density and mental health in young Australian women: the Safe-D study |
title_fullStr |
Vitamin D status, bone mineral density and mental health in young Australian women: the Safe-D study |
title_full_unstemmed |
Vitamin D status, bone mineral density and mental health in young Australian women: the Safe-D study |
title_sort |
vitamin d status, bone mineral density and mental health in young australian women: the safe-d study |
publisher |
PAGEPress Publications |
series |
Journal of Public Health Research |
issn |
2279-9028 2279-9036 |
publishDate |
2015-11-01 |
description |
<em>Background</em>. Vitamin D deficiency has been associated with both poor bone health and mental ill-health. More recently, a number of studies have found individuals with depressive symptoms tend to have reduced bone mineral density. To explore the interrelationships between vitamin D status, bone mineral density and mental-ill health we are assessing a range of clinical, behavioural and lifestyle factors in young women (Part A of the Safe-D study). <br /><em>Design and methods.</em> Part A of the Safe-D study is a cross-sectional study aiming to recruit 468 young females aged 16-25 years living in Victoria, Australia, through Facebook advertising. Participants are required to complete an extensive, online questionnaire, wear an ultra-violet dosimeter for 14 consecutive days and attend a study site visit. Outcome measures include areal bone mineral measures at the lumbar spine, total hip and whole body, as well as soft tissue composition using dual energy x-ray absorptiometry. Trabecular and cortical volumetric bone density at the tibia is measured using peripheral quantitative computed tomography. Other tests include serum 25-hydroxyvitamin D, serum biochemistry and a range of health markers. Details of mood disorder/s and depressive and anxiety symptoms are obtained by self-report. Cutaneous melanin density is measured by spectrophotometry. <br /><em>Expected impact.</em> The findings of this cross-sectional study will have implications for health promotion in young women and for clinical care of those with vitamin D deficiency and/or mental ill-health. Optimising both vitamin D status and mental health may protect against poor bone health and fractures in later life. |
topic |
Vitamin D bone mineral density osteoporosis depression dual energy x-ray absorptiometry |
url |
http://www.jphres.org/index.php/jphres/article/view/594 |
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