Cannabis-based medicines and the perioperative physician
Abstract The increasing availability of cannabis for both recreational and medicinal purposes means that anaesthetists will encounter an increasing number of patients taking cannabis-based medications. The existing evidence base is conflicted and incomplete regarding the indications, interactions an...
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Online Access: | https://doi.org/10.1186/s13741-019-0127-x |
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doaj-75c0107b15ee413ab06cb7a3c2d4cd172020-12-06T12:06:34ZengBMCPerioperative Medicine2047-05252019-12-018111510.1186/s13741-019-0127-xCannabis-based medicines and the perioperative physicianPatrick Tapley0Suzanne Kellett1Department of Anaesthesia, Sunnybrook Health Sciences CentreShackleton Department of Anaesthesia, University Hospital SouthamptonAbstract The increasing availability of cannabis for both recreational and medicinal purposes means that anaesthetists will encounter an increasing number of patients taking cannabis-based medications. The existing evidence base is conflicted and incomplete regarding the indications, interactions and long-term effects of these substances. Globally, most doctors have had little education regarding the pharmacology of cannabis-based medicines, despite the endocannabinoid system being one of the most widespread in the human body. Much is unknown, and much is to be decided, including clarifying definitions and nomenclature, and therapeutic indications and dosing. Anaesthetists, Intensivists, Pain and Perioperative physicians will want to contribute to this evidence base and attempt to harness such therapeutic benefits in terms of pain relief and opiate-avoidance, anti-emesis and seizure control. We present a summary of the pharmacology of cannabis-based medicines including anaesthetic interactions and implications, to assist colleagues encountering these medicines in clinical practice.https://doi.org/10.1186/s13741-019-0127-xPharmacologyCannabisCannabinoidsMedical marijuana |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Patrick Tapley Suzanne Kellett |
spellingShingle |
Patrick Tapley Suzanne Kellett Cannabis-based medicines and the perioperative physician Perioperative Medicine Pharmacology Cannabis Cannabinoids Medical marijuana |
author_facet |
Patrick Tapley Suzanne Kellett |
author_sort |
Patrick Tapley |
title |
Cannabis-based medicines and the perioperative physician |
title_short |
Cannabis-based medicines and the perioperative physician |
title_full |
Cannabis-based medicines and the perioperative physician |
title_fullStr |
Cannabis-based medicines and the perioperative physician |
title_full_unstemmed |
Cannabis-based medicines and the perioperative physician |
title_sort |
cannabis-based medicines and the perioperative physician |
publisher |
BMC |
series |
Perioperative Medicine |
issn |
2047-0525 |
publishDate |
2019-12-01 |
description |
Abstract The increasing availability of cannabis for both recreational and medicinal purposes means that anaesthetists will encounter an increasing number of patients taking cannabis-based medications. The existing evidence base is conflicted and incomplete regarding the indications, interactions and long-term effects of these substances. Globally, most doctors have had little education regarding the pharmacology of cannabis-based medicines, despite the endocannabinoid system being one of the most widespread in the human body. Much is unknown, and much is to be decided, including clarifying definitions and nomenclature, and therapeutic indications and dosing. Anaesthetists, Intensivists, Pain and Perioperative physicians will want to contribute to this evidence base and attempt to harness such therapeutic benefits in terms of pain relief and opiate-avoidance, anti-emesis and seizure control. We present a summary of the pharmacology of cannabis-based medicines including anaesthetic interactions and implications, to assist colleagues encountering these medicines in clinical practice. |
topic |
Pharmacology Cannabis Cannabinoids Medical marijuana |
url |
https://doi.org/10.1186/s13741-019-0127-x |
work_keys_str_mv |
AT patricktapley cannabisbasedmedicinesandtheperioperativephysician AT suzannekellett cannabisbasedmedicinesandtheperioperativephysician |
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