Critical role of SDF-1/CXCR4 signaling pathway in stem cell homing in the deafened rat cochlea after acoustic trauma

Critical role of SDF-1/CXCR4 signaling pathway in stem cell homing in the deafened rat cochlea after acoustic trauma

Previous animal studies have shown that stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor-4 (CXCR4) signaling pathway plays an important role in the targeted migration of bone marrow-derived mesenchymal stem cells (BMSCs) to the injured area. In the present study, we aimed to investigate...

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Bibliographic Details
Main Authors: Ali Asghar Peyvandi, Navid Ahmady Roozbahany, Hassan Peyvandi, Hojjat-Allah Abbaszadeh, Niloofar Majdinasab, Mohammad Faridan, Somayeh Niknazar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; stem cells; migration; SDF-1/ CXCR4 axis; noise-induced hearing loss; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=1;spage=154;epage=160;aulast=Peyvandi

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