Unexpected Evolution of Lesion-Recognition Modules in Eukaryotic NER and Kinetoplast DNA Dynamics Proteins from Bacterial Mobile Elements
Summary: The provenance of several components of major uniquely eukaryotic molecular machines are increasingly being traced back to prokaryotic biological conflict systems. Here, we demonstrate that the N-terminal single-stranded DNA-binding domain from the anti-restriction protein ArdC, deployed by...
Main Authors: | Arunkumar Krishnan, A. Maxwell Burroughs, Lakshminarayan M. Iyer, L. Aravind |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-11-01
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Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004218301767 |
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