Meiotic recombination in human oocytes.

Meiotic recombination in human oocytes.

Studies of human trisomies indicate a remarkable relationship between abnormal meiotic recombination and subsequent nondisjunction at maternal meiosis I or II. Specifically, failure to recombine or recombination events located either too near to or too far from the centromere have been linked to the...

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Main Authors: Edith Y Cheng, Patricia A Hunt, Theresa A Naluai-Cecchini, Corrine L Fligner, Victor Y Fujimoto, Tanya L Pasternack, Jackie M Schwartz, Jody E Steinauer, Tracey J Woodruff, Sheila M Cherry, Terah A Hansen, Rhea U Vallente, Karl W Broman, Terry J Hassold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2735652?pdf=render

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