Association between MTHFR C677T/A1298C and susceptibility to autism spectrum disorders: a meta-analysis

Association between MTHFR C677T/A1298C and susceptibility to autism spectrum disorders: a meta-analysis

Abstract Background Autism spectrum disorder (ASD) is becoming increasingly prevalent of late. Methylenetetrahydrofolate reductase (MTHFR) has a significant role in folate metabolism. Owing to the inconsistencies and inconclusiveness on the association between MTHFR single nucleotide polymorphism (S...

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Bibliographic Details
Main Authors: Yan Li, Shuang Qiu, Jikang Shi, Yanbo Guo, Zhijun Li, Yi Cheng, Yawen Liu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Pediatrics
Subjects:
Methylenetetrahydrofolate reductase
Autism spectrum disorder
Single nucleotide polymorphisms
Genetic models
Meta-analysis
Online Access:http://link.springer.com/article/10.1186/s12887-020-02330-3

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