Biochemical Markers of Lipid Metabolism Disorders in Children with Hepatic Steatosis
Peculiarities of blood lipids were studied in children with functional disorders of the biliary tract (FDBT) and liver steatosis. We have examined 28 children aged 10 to 17 years, who sought medical help in the department of pediatric gastroenterology of State institution «Institute of gastroenterol...
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2015-11-01
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doaj-760b82e674fe4b918b639acf86f179d82020-11-24T22:34:27ZengPublishing House ZaslavskyZdorovʹe Rebenka2224-05512307-11682015-11-01108.68384210.22141/2224-0551.8.68.2015.7514975149Biochemical Markers of Lipid Metabolism Disorders in Children with Hepatic SteatosisN.Yu. Zavhorodnia0S.O. Babii1I.A. Klenina2I.Yu. Skyrda3O.P. Petishko4State Institution «Institute of Gastroenterology of National Academy of Medical Sciences of Ukraine», DnipropetrovskState Institution «Institute of Gastroenterology of National Academy of Medical Sciences of Ukraine», DnipropetrovskState Institution «Institute of Gastroenterology of National Academy of Medical Sciences of Ukraine», DnipropetrovskState Institution «Institute of Gastroenterology of National Academy of Medical Sciences of Ukraine», DnipropetrovskState Institution «Institute of Gastroenterology of National Academy of Medical Sciences of Ukraine», DnipropetrovskPeculiarities of blood lipids were studied in children with functional disorders of the biliary tract (FDBT) and liver steatosis. We have examined 28 children aged 10 to 17 years, who sought medical help in the department of pediatric gastroenterology of State institution «Institute of gastroenterology of National academy of medical sciences of Ukraine». The presence of steatosis was determined by means of liver transient elastography with the study of controlled parameter of ultrasonic attenuation. According to the findings, we have formed two groups: I group — 17 children with FDBT without steatosis; II group — 11 children with FDBT and steatosis. As research markers of serum lipids, we have used the content of total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, and atherogenic factor was calculated. It was found that children with FDBT are characterized by dyslipidemia, which manifests itself in the reduction of very low-density lipoprotein cholesterol, increase of low-density lipoprotein cholesterol and atherogenic factor. Signs of metabolic syndrome are characteristic of the blood lipids of children with steatosis.http://childshealth.zaslavsky.com.ua/article/view/75149lipid metabolismhepatic steatosischildren |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
N.Yu. Zavhorodnia S.O. Babii I.A. Klenina I.Yu. Skyrda O.P. Petishko |
spellingShingle |
N.Yu. Zavhorodnia S.O. Babii I.A. Klenina I.Yu. Skyrda O.P. Petishko Biochemical Markers of Lipid Metabolism Disorders in Children with Hepatic Steatosis Zdorovʹe Rebenka lipid metabolism hepatic steatosis children |
author_facet |
N.Yu. Zavhorodnia S.O. Babii I.A. Klenina I.Yu. Skyrda O.P. Petishko |
author_sort |
N.Yu. Zavhorodnia |
title |
Biochemical Markers of Lipid Metabolism Disorders in Children with Hepatic Steatosis |
title_short |
Biochemical Markers of Lipid Metabolism Disorders in Children with Hepatic Steatosis |
title_full |
Biochemical Markers of Lipid Metabolism Disorders in Children with Hepatic Steatosis |
title_fullStr |
Biochemical Markers of Lipid Metabolism Disorders in Children with Hepatic Steatosis |
title_full_unstemmed |
Biochemical Markers of Lipid Metabolism Disorders in Children with Hepatic Steatosis |
title_sort |
biochemical markers of lipid metabolism disorders in children with hepatic steatosis |
publisher |
Publishing House Zaslavsky |
series |
Zdorovʹe Rebenka |
issn |
2224-0551 2307-1168 |
publishDate |
2015-11-01 |
description |
Peculiarities of blood lipids were studied in children with functional disorders of the biliary tract (FDBT) and liver steatosis. We have examined 28 children aged 10 to 17 years, who sought medical help in the department of pediatric gastroenterology of State institution «Institute of gastroenterology of National academy of medical sciences of Ukraine». The presence of steatosis was determined by means of liver transient elastography with the study of controlled parameter of ultrasonic attenuation. According to the findings, we have formed two groups: I group — 17 children with FDBT without steatosis; II group — 11 children with FDBT and steatosis. As research markers of serum lipids, we have used the content of total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, and atherogenic factor was calculated. It was found that children with FDBT are characterized by dyslipidemia, which manifests itself in the reduction of very low-density lipoprotein cholesterol, increase of low-density lipoprotein cholesterol and atherogenic factor. Signs of metabolic syndrome are characteristic of the blood lipids of children with steatosis. |
topic |
lipid metabolism hepatic steatosis children |
url |
http://childshealth.zaslavsky.com.ua/article/view/75149 |
work_keys_str_mv |
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