Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid Regulation

Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid Regulation

In the past few years expanding knowledge has been accumulated about the role of microRNAs (miRNAs) not only in hematopoiesis and cancer, but also in inflammatory and infectious diseases. Regarding myeloid cells, our knowledge is relatively insufficient, therefore we intended to collect the availabl...

Full description

Bibliographic Details
Main Authors: Anna B. Gilicze, Zoltán Wiener, Sára Tóth, Edit Buzás, Éva Pállinger, Franco H. Falcone, András Falus
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/870267
id doaj-762e0fd36b9c4c73a47e1dc3a8fb363a
record_format Article
spelling doaj-762e0fd36b9c4c73a47e1dc3a8fb363a2020-11-24T21:45:56ZengHindawi LimitedBioMed Research International2314-61332314-61412014-01-01201410.1155/2014/870267870267Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid RegulationAnna B. Gilicze0Zoltán Wiener1Sára Tóth2Edit Buzás3Éva Pállinger4Franco H. Falcone5András Falus6Department of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest 1089, HungaryDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest 1089, HungaryDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest 1089, HungaryDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest 1089, HungaryDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest 1089, HungaryDivision of Molecular & Cellular Science, The School of Pharmacy, University Park Science Road, Nottingham NG7 2RD, UKDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest 1089, HungaryIn the past few years expanding knowledge has been accumulated about the role of microRNAs (miRNAs) not only in hematopoiesis and cancer, but also in inflammatory and infectious diseases. Regarding myeloid cells, our knowledge is relatively insufficient, therefore we intended to collect the available data of miRNA profiles of myeloid cells. In addition to a rather general myeloid regulator miR-223, two other miRNAs seem to be useful subjects in understanding of myeloid miRNA biology: miR-27a and miR-652. We review functions of these three miRNAs and other myeloid miRNAs focusing on their roles in monocytes, neutrophils, eosinophils, basophils and mast cells.http://dx.doi.org/10.1155/2014/870267
collection DOAJ
language English
format Article
sources DOAJ
author Anna B. Gilicze
Zoltán Wiener
Sára Tóth
Edit Buzás
Éva Pállinger
Franco H. Falcone
András Falus
spellingShingle Anna B. Gilicze
Zoltán Wiener
Sára Tóth
Edit Buzás
Éva Pállinger
Franco H. Falcone
András Falus
Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid Regulation
BioMed Research International
author_facet Anna B. Gilicze
Zoltán Wiener
Sára Tóth
Edit Buzás
Éva Pállinger
Franco H. Falcone
András Falus
author_sort Anna B. Gilicze
title Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid Regulation
title_short Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid Regulation
title_full Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid Regulation
title_fullStr Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid Regulation
title_full_unstemmed Myeloid-Derived microRNAs, miR-223, miR27a, and miR-652, Are Dominant Players in Myeloid Regulation
title_sort myeloid-derived micrornas, mir-223, mir27a, and mir-652, are dominant players in myeloid regulation
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2014-01-01
description In the past few years expanding knowledge has been accumulated about the role of microRNAs (miRNAs) not only in hematopoiesis and cancer, but also in inflammatory and infectious diseases. Regarding myeloid cells, our knowledge is relatively insufficient, therefore we intended to collect the available data of miRNA profiles of myeloid cells. In addition to a rather general myeloid regulator miR-223, two other miRNAs seem to be useful subjects in understanding of myeloid miRNA biology: miR-27a and miR-652. We review functions of these three miRNAs and other myeloid miRNAs focusing on their roles in monocytes, neutrophils, eosinophils, basophils and mast cells.
url http://dx.doi.org/10.1155/2014/870267
work_keys_str_mv AT annabgilicze myeloidderivedmicrornasmir223mir27aandmir652aredominantplayersinmyeloidregulation
AT zoltanwiener myeloidderivedmicrornasmir223mir27aandmir652aredominantplayersinmyeloidregulation
AT saratoth myeloidderivedmicrornasmir223mir27aandmir652aredominantplayersinmyeloidregulation
AT editbuzas myeloidderivedmicrornasmir223mir27aandmir652aredominantplayersinmyeloidregulation
AT evapallinger myeloidderivedmicrornasmir223mir27aandmir652aredominantplayersinmyeloidregulation
AT francohfalcone myeloidderivedmicrornasmir223mir27aandmir652aredominantplayersinmyeloidregulation
AT andrasfalus myeloidderivedmicrornasmir223mir27aandmir652aredominantplayersinmyeloidregulation
_version_ 1725903232808517632

Similar Items