miR-222 Suppresses Immature Porcine Sertoli Cell Growth by Targeting the GRB10 Gene Through Inactivating the PI3K/AKT Signaling Pathway

miR-222 Suppresses Immature Porcine Sertoli Cell Growth by Targeting the GRB10 Gene Through Inactivating the PI3K/AKT Signaling Pathway

Sertoli cells are central and essential coordinators of spermatogenesis. Accumulating evidence has demonstrated that miRNAs participate in the regulation of Sertoli cell growth. However, the functions and the regulatory mechanisms of miRNAs in Sertoli cells of domestic animals remain largely unknown...

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Bibliographic Details
Main Authors: Hui Luo, Fuzhi Peng, Bo Weng, Xiangwei Tang, Yao Chen, Anqi Yang, Bin Chen, Maoliang Ran
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Genetics
Subjects:
Sertoli cells
porcine
proliferation
miR-222
GRB10
PI3K/AKT signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.581593/full

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