Role of the Cysteinyl Leukotrienes in the Pathogenesis and Progression of Cardiovascular Diseases
Cysteinyl leukotrienes (CysLTs) are potent lipid inflammatory mediators synthesized from arachidonic acid, through the 5-lipoxygenase (5-LO) pathway. Owing to their properties, CysLTs play a crucial role in the pathogenesis of inflammation; therefore, CysLT modifiers as synthesis inhibitors or recep...
Main Authors: | Francesca Colazzo, Paolo Gelosa, Elena Tremoli, Luigi Sironi, Laura Castiglioni |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2017/2432958 |
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