EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME
The article presents a case of a successful canakinumab application (preparation of monoclonal antibodies to 1 interleukin) for undifferentiated autoinflammatory syndrome in a patient with refractoriness to oral glucocorticosteroids and genetically engineered biological drugs with a different action...
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| Language: | English |
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"Paediatrician" Publishers LLC
2016-11-01
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| Series: | Voprosy Sovremennoj Pediatrii |
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| Online Access: | https://vsp.spr-journal.ru/jour/article/view/1677 |
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doaj-7677bc8142954b3b97092bf87c2fc41c2021-07-28T21:15:44Zeng"Paediatrician" Publishers LLC Voprosy Sovremennoj Pediatrii1682-55271682-55352016-11-0115552252610.15690/vsp.v15i5.16271634EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROMETatyana V. Sleptsova0Еkaterina I. Alexeeva1Тatyana М. Bzarova2Kirill V. Savostyanov3Аlexander A. Pushkov4Kseniya B. Isaeva5Rina V. Denisova6Оlga L. Lomakina7Scientific Center of Children’s HealthScientific Center of Children’s Health; Sechenov First Moscow State Medical UniversityScientific Center of Children’s Health; Sechenov First Moscow State Medical UniversityScientific Center of Children’s HealthScientific Center of Children’s HealthScientific Center of Children’s HealthScientific Center of Children’s HealthScientific Center of Children’s HealthThe article presents a case of a successful canakinumab application (preparation of monoclonal antibodies to 1 interleukin) for undifferentiated autoinflammatory syndrome in a patient with refractoriness to oral glucocorticosteroids and genetically engineered biological drugs with a different action mechanisms. After 8 weeks of canakinumab therapy, systemic manifestations were cropped, and laboratory parameters of the disease activity were normalized. During the entire care period (12 months), neither serious adverse events nor increased incidence of acute respiratory infections have been reported.https://vsp.spr-journal.ru/jour/article/view/1677childrenautoinflammatory syndromecanakinumabclinical case |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Tatyana V. Sleptsova Еkaterina I. Alexeeva Тatyana М. Bzarova Kirill V. Savostyanov Аlexander A. Pushkov Kseniya B. Isaeva Rina V. Denisova Оlga L. Lomakina |
| spellingShingle |
Tatyana V. Sleptsova Еkaterina I. Alexeeva Тatyana М. Bzarova Kirill V. Savostyanov Аlexander A. Pushkov Kseniya B. Isaeva Rina V. Denisova Оlga L. Lomakina EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME Voprosy Sovremennoj Pediatrii children autoinflammatory syndrome canakinumab clinical case |
| author_facet |
Tatyana V. Sleptsova Еkaterina I. Alexeeva Тatyana М. Bzarova Kirill V. Savostyanov Аlexander A. Pushkov Kseniya B. Isaeva Rina V. Denisova Оlga L. Lomakina |
| author_sort |
Tatyana V. Sleptsova |
| title |
EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME |
| title_short |
EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME |
| title_full |
EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME |
| title_fullStr |
EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME |
| title_full_unstemmed |
EXPERIENCE OF THE SUCCESSFUL CANAKINUMAB TREATMENT OF A PATIENT WITH UNDIFFERENTIATED AUTOINFLAMMATORY SYNDROME |
| title_sort |
experience of the successful canakinumab treatment of a patient with undifferentiated autoinflammatory syndrome |
| publisher |
"Paediatrician" Publishers LLC |
| series |
Voprosy Sovremennoj Pediatrii |
| issn |
1682-5527 1682-5535 |
| publishDate |
2016-11-01 |
| description |
The article presents a case of a successful canakinumab application (preparation of monoclonal antibodies to 1 interleukin) for undifferentiated autoinflammatory syndrome in a patient with refractoriness to oral glucocorticosteroids and genetically engineered biological drugs with a different action mechanisms. After 8 weeks of canakinumab therapy, systemic manifestations were cropped, and laboratory parameters of the disease activity were normalized. During the entire care period (12 months), neither serious adverse events nor increased incidence of acute respiratory infections have been reported. |
| topic |
children autoinflammatory syndrome canakinumab clinical case |
| url |
https://vsp.spr-journal.ru/jour/article/view/1677 |
| work_keys_str_mv |
AT tatyanavsleptsova experienceofthesuccessfulcanakinumabtreatmentofapatientwithundifferentiatedautoinflammatorysyndrome AT ekaterinaialexeeva experienceofthesuccessfulcanakinumabtreatmentofapatientwithundifferentiatedautoinflammatorysyndrome AT tatyanambzarova experienceofthesuccessfulcanakinumabtreatmentofapatientwithundifferentiatedautoinflammatorysyndrome AT kirillvsavostyanov experienceofthesuccessfulcanakinumabtreatmentofapatientwithundifferentiatedautoinflammatorysyndrome AT alexanderapushkov experienceofthesuccessfulcanakinumabtreatmentofapatientwithundifferentiatedautoinflammatorysyndrome AT kseniyabisaeva experienceofthesuccessfulcanakinumabtreatmentofapatientwithundifferentiatedautoinflammatorysyndrome AT rinavdenisova experienceofthesuccessfulcanakinumabtreatmentofapatientwithundifferentiatedautoinflammatorysyndrome AT olgallomakina experienceofthesuccessfulcanakinumabtreatmentofapatientwithundifferentiatedautoinflammatorysyndrome |
| _version_ |
1721261374692130816 |