Mechanisms of chromosomal rearrangement in the human genome
<p>Abstract</p> <p>Many human cancers are associated with characteristic chromosomal rearrangements, especially hematopoietic cancers such as leukemias and lymphomas. The first and most critical step in the rearrangement process is the induction of two DNA double-strand breaks (DSB...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2010-02-01
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| Series: | BMC Genomics |