Anticoagulation and pediatric extracorporeal life support (ECLS). A review of current practice and recommendations
Pediatric ECLS and advances in ECMO management have truly evolved as a critical management strategy with improved outcomes and holistic survival over the last two decades. Excessive bleeding and thrombosis still constitute the principal cause of morbidity and mortality. The non-biological surface of...
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Wolters Kluwer Medknow Publications
2017-01-01
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doaj-76c1b0fe44e6441abac0514ad4917fcc2020-11-25T03:56:29ZengWolters Kluwer Medknow PublicationsJournal of Pediatric Critical Care2349-65922455-70992017-01-0142677510-21304/2017-0402-00181Anticoagulation and pediatric extracorporeal life support (ECLS). A review of current practice and recommendationsVishal SinghAjay GuptaBijender S BaliRajesh SharmaPediatric ECLS and advances in ECMO management have truly evolved as a critical management strategy with improved outcomes and holistic survival over the last two decades. Excessive bleeding and thrombosis still constitute the principal cause of morbidity and mortality. The non-biological surface of an extracorporeal circuit provokes a massive inflammatory response initiating consumption and activation of procoagulant and anticoagulant components. Besides the vast difference in neonatal and adult coagulation and transfusion requirements, render anticoagulation on ECMO as a major determinant in reducing morbidity. Anticoagulation is a fluid science and it is imperative that caregivers are aware of the existing anticoagulants with their advantages and disadvantages and advances in monitoring tools to ensure that morbidity is minimized with better outcomes.http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2017;volume=4;issue=2;spage=67;epage=75;aulast=Singhanticoagulationextracorporeal membrane oxygenationbleedingthrombosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Vishal Singh Ajay Gupta Bijender S Bali Rajesh Sharma |
spellingShingle |
Vishal Singh Ajay Gupta Bijender S Bali Rajesh Sharma Anticoagulation and pediatric extracorporeal life support (ECLS). A review of current practice and recommendations Journal of Pediatric Critical Care anticoagulation extracorporeal membrane oxygenation bleeding thrombosis |
author_facet |
Vishal Singh Ajay Gupta Bijender S Bali Rajesh Sharma |
author_sort |
Vishal Singh |
title |
Anticoagulation and pediatric extracorporeal life support (ECLS). A review of current practice and recommendations |
title_short |
Anticoagulation and pediatric extracorporeal life support (ECLS). A review of current practice and recommendations |
title_full |
Anticoagulation and pediatric extracorporeal life support (ECLS). A review of current practice and recommendations |
title_fullStr |
Anticoagulation and pediatric extracorporeal life support (ECLS). A review of current practice and recommendations |
title_full_unstemmed |
Anticoagulation and pediatric extracorporeal life support (ECLS). A review of current practice and recommendations |
title_sort |
anticoagulation and pediatric extracorporeal life support (ecls). a review of current practice and recommendations |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Pediatric Critical Care |
issn |
2349-6592 2455-7099 |
publishDate |
2017-01-01 |
description |
Pediatric ECLS and advances in ECMO management have truly evolved as a critical management strategy with improved outcomes and holistic survival over the last two decades. Excessive bleeding and thrombosis still constitute the principal cause of morbidity and mortality. The non-biological surface of an extracorporeal circuit provokes a massive inflammatory response initiating consumption and activation of procoagulant and anticoagulant components. Besides the vast difference in neonatal and adult coagulation and transfusion requirements, render anticoagulation on ECMO as a major determinant in reducing morbidity. Anticoagulation is a fluid science and it is imperative that caregivers are aware of the existing anticoagulants with their advantages and disadvantages and advances in monitoring tools to ensure that morbidity is minimized with better outcomes. |
topic |
anticoagulation extracorporeal membrane oxygenation bleeding thrombosis |
url |
http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2017;volume=4;issue=2;spage=67;epage=75;aulast=Singh |
work_keys_str_mv |
AT vishalsingh anticoagulationandpediatricextracorporeallifesupporteclsareviewofcurrentpracticeandrecommendations AT ajaygupta anticoagulationandpediatricextracorporeallifesupporteclsareviewofcurrentpracticeandrecommendations AT bijendersbali anticoagulationandpediatricextracorporeallifesupporteclsareviewofcurrentpracticeandrecommendations AT rajeshsharma anticoagulationandpediatricextracorporeallifesupporteclsareviewofcurrentpracticeandrecommendations |
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1724464735172165632 |