Cell-Type-Specific Proteogenomic Signal Diffusion for Integrating Multi-Omics Data Predicts Novel Schizophrenia Risk Genes
Summary: Accumulation of diverse types of omics data on schizophrenia (SCZ) requires a systems approach to model the interplay between genome, transcriptome, and proteome. We introduce Markov affinity-based proteogenomic signal diffusion (MAPSD), a method to model intra-cellular protein trafficking...
Main Authors: | Abolfazl Doostparast Torshizi, Jubao Duan, Kai Wang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-09-01
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Series: | Patterns |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666389920301197 |
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