Kikuchi-Fujimoto Disease: A Case Report
We describe a rare but typical case of Kikuchi-Fujimoto disease (KFD). Two subcutaneous nodules appeared suddenly on the right of the neck of a 15-year-old girl. Microscopy of a surgical specimen of the larger nodule showed necrotizing lymphadenitis. Prompt treatment with mepirizole resulted in the...
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2003-05-01
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doaj-76e31b9770a04c3a9041124812cc1fbb2020-11-25T02:19:12ZengWileyKaohsiung Journal of Medical Sciences1607-551X2003-05-0119524625010.1016/S1607-551X(09)70432-2Kikuchi-Fujimoto Disease: A Case ReportChih-Hung LeeShih-Tsung ChengWe describe a rare but typical case of Kikuchi-Fujimoto disease (KFD). Two subcutaneous nodules appeared suddenly on the right of the neck of a 15-year-old girl. Microscopy of a surgical specimen of the larger nodule showed necrotizing lymphadenitis. Prompt treatment with mepirizole resulted in the disappearance of the smaller nodule. No recurrence was noted during 6 months of follow-up. KFD is a rare, self-limiting, necrotizing histiocytic lymphadenitis that needs to be differentiated from malignant lymphoma. Any nodal biopsy showing fragmented nuclei, necrosis, and karyorrhexis without prominent neutrophils should alert the physician to consideration of KFD, especially in a young woman presenting with cervical lymphadenopathy.http://www.sciencedirect.com/science/article/pii/S1607551X09704322Kikuchi-Fujimoto diseasenecrotizing histiocytic lymphadenitis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chih-Hung Lee Shih-Tsung Cheng |
spellingShingle |
Chih-Hung Lee Shih-Tsung Cheng Kikuchi-Fujimoto Disease: A Case Report Kaohsiung Journal of Medical Sciences Kikuchi-Fujimoto disease necrotizing histiocytic lymphadenitis |
author_facet |
Chih-Hung Lee Shih-Tsung Cheng |
author_sort |
Chih-Hung Lee |
title |
Kikuchi-Fujimoto Disease: A Case Report |
title_short |
Kikuchi-Fujimoto Disease: A Case Report |
title_full |
Kikuchi-Fujimoto Disease: A Case Report |
title_fullStr |
Kikuchi-Fujimoto Disease: A Case Report |
title_full_unstemmed |
Kikuchi-Fujimoto Disease: A Case Report |
title_sort |
kikuchi-fujimoto disease: a case report |
publisher |
Wiley |
series |
Kaohsiung Journal of Medical Sciences |
issn |
1607-551X |
publishDate |
2003-05-01 |
description |
We describe a rare but typical case of Kikuchi-Fujimoto disease (KFD). Two subcutaneous nodules appeared suddenly on the right of the neck of a 15-year-old girl. Microscopy of a surgical specimen of the larger nodule showed necrotizing lymphadenitis. Prompt treatment with mepirizole resulted in the disappearance of the smaller nodule. No recurrence was noted during 6 months of follow-up. KFD is a rare, self-limiting, necrotizing histiocytic lymphadenitis that needs to be differentiated from malignant lymphoma. Any nodal biopsy showing fragmented nuclei, necrosis, and karyorrhexis without prominent neutrophils should alert the physician to consideration of KFD, especially in a young woman presenting with cervical lymphadenopathy. |
topic |
Kikuchi-Fujimoto disease necrotizing histiocytic lymphadenitis |
url |
http://www.sciencedirect.com/science/article/pii/S1607551X09704322 |
work_keys_str_mv |
AT chihhunglee kikuchifujimotodiseaseacasereport AT shihtsungcheng kikuchifujimotodiseaseacasereport |
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1724877731704864768 |