Screening, Vaccination Uptake and Linkage to Care for Hepatitis B Virus among Health Care Workers in Rural Sierra Leone

• Main Authors: Musa Bangura, Anna Frühauf, Michael Mhango, Daniel Lavallie, Vicky Reed, Marta Patiño Rodriguez, Samuel Juana Smith, Sulaiman Lakoh, Emmanuel Ibrahim-Sayo, Sorie Conteh, Marta Lado, Chiyembekezo Kachimanga
• Format: Article
• Language: English
• Published: MDPI AG 2021-04-01
• Series: Tropical Medicine and Infectious Disease
• Subjects: Sierra Leone; health care workers; hepatitis B virus; chronic liver disease; screening; vaccination
• Online Access: https://www.mdpi.com/2414-6366/6/2/65

This study reports on the prevalence and risk factors of chronic HBV among health care workers (HCWs) in a rural secondary hospital in Sierra Leone. Additionally, data on the uptake of HBV vaccination among negatively tested HCWs and on the linkage to care among positively tested HCWs are presented. In December 2019, 781 HCWs were invited to a screening and vaccination campaign at Koidu Government Hospital in Kono District. For each HCW, demographic information and data on their HBV risk history were captured, followed by a hepatitis B surface antigen (HBsAg) test. HCWs with a negative test result were offered an HBV vaccine on the same day, after one and six months. HCWs that were HBsAg positive were linked to a free HBV clinic. In total, 80% (632) of HCWs were screened. Among the screened, 97% had never received an HBV vaccine and 10.3% (n = 65) had chronic HBV. The following characteristics were associated with being HBsAg positive: aged less than 30 years old (aOR 2.17, CI 1.16–4.03, <i>p</i> = 0.01), male gender (aOR 2.0, CI 1.06–3.78, <i>p</i> = 0.03), working experience of 1–4 years (aOR 3.99, CI 1.15–13.73, <i>p</i> = 0.03) and over 9 years (aOR 6.16, CI 1.41–26.9, <i>p</i> = 0.02). For HBsAg-negative HCWs (n = 567), 99.8% (n = 566), 97.5% (n = 553) and 82.7% (n = 469) received their first, second and third dose of the vaccine, respectively. For HBsAg-positive HCWs (n = 65), 73.9% (n = 48) were successfully linked to an HBV clinic for further care. Most HCWs are unvaccinated for HBV, and the HBV prevalence amongst this at-risk group is high. Uptake of vaccination and linkage to care was successful.