Ultrasound can detect macroscopically undetectable changes in osteoarthritis reflecting the superficial histological and biochemical degeneration: ex vivo study of rabbit and human cartilage.

Recognizing subtle cartilage changes in the preclinical stage of osteoarthritis (OA) is essential for early diagnosis. To this end, the ability of the ultrasound signal intensity to detect macroscopically undetectable cartilage change was investigated. In this study, cartilage of rabbit OA model and...

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Bibliographic Details
Main Authors: Kohei Nishitani, Masahiko Kobayashi, Hiroshi Kuroki, Koji Mori, Takaaki Shirai, Tsuyoshi Satake, Shinnichiro Nakamura, Ryuzo Arai, Yasuaki Nakagawa, Takashi Nakamura, Shuichi Matsuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3931779?pdf=render