Developing Gram-negative bacteria for the secretion of heterologous proteins

Developing Gram-negative bacteria for the secretion of heterologous proteins

Abstract Gram-negative bacteria are attractive hosts for recombinant protein production because they are fast growing, easy to manipulate, and genetically stable in large cultures. However, the utility of these microbes would expand if they also could secrete the product at commercial scales. Secret...

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Bibliographic Details
Main Authors: Lisa Ann Burdette, Samuel Alexander Leach, Han Teng Wong, Danielle Tullman-Ercek
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Microbial Cell Factories
Subjects:
Protein secretion
Bacterial secretion systems
Recombinant protein
Online Access:http://link.springer.com/article/10.1186/s12934-018-1041-5

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