Three-dimensionally printed polycaprolactone/multicomponent bioactive glass scaffolds for potential application in bone tissue engineering

Over the last years, three-dimensional (3D) printing has been successfully applied to produce suitable substitutes for treating bone defects. In this work, 3D printed composite scaffolds of polycaprolactone (PCL) and strontium (Sr)- and cobalt (Co)-doped multi-component melt-derived bioactive glasse...

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Bibliographic Details
Main Authors: Fathi Amirhosein, Kermani Farzad, Behnamghader Aliasghar, Banijamali Sara, Mozafari Masoud, Baino Francesco, Kargozar Saeid
Format: Article
Language:English
Published: Sciendo 2020-12-01
Series:Biomedical Glasses
Subjects:
Online Access:https://doi.org/10.1515/bglass-2020-0006
Description
Summary:Over the last years, three-dimensional (3D) printing has been successfully applied to produce suitable substitutes for treating bone defects. In this work, 3D printed composite scaffolds of polycaprolactone (PCL) and strontium (Sr)- and cobalt (Co)-doped multi-component melt-derived bioactive glasses (BGs) were prepared for bone tissue engineering strategies. For this purpose, 30% of as-prepared BG particles (size <38 μm) were incorporated into PCL, and then the obtained composite mix was introduced into a 3D printing machine to fabricate layer-by-layer porous structures with the size of 12 × 12 × 2 mm3.
ISSN:2299-3932