Expression of the pluripotency transcription factor OCT4 in the normal and aberrant mammary gland

Expression of the pluripotency transcription factor OCT4 in the normal and aberrant mammary gland

Breast cancers with lactating features, some of which are associated with pregnancy and lactation, are often poorly differentiated, lack estrogen receptor, progesterone receptor and HER2 expression and have high mortality. Very little is known about the molecular mechanisms that drive uncontrolled c...

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Bibliographic Details
Main Authors: Foteini eHassiotou, Anna eHepworth, Adriana eBeltran, Michelle eMathews, Alison eStuebe, Peter eHartmann, Luis eFilgueira, Pilar eBlancafort
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Oncology
Subjects:
Transcription Factors
breast cancer
Cancer stem cell
proliferation
mammary gland
self-renewal
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00079/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00079/full

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