Arthritis as a presentation of acute leukemia

A 14 year old boy presented with 3 months history of low back pain as well as pain and swelling of both knee joints. The pain was inflammatory in nature. He was thoroughly evaluated but no underlying cause was detected. However, the boy was treated with NSAIDs and sulphasalazine. A few weeks later...

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Main Authors: Md. Abdul Aziz, Surozit Kumar Sarkar, Farzana Rahman, Shafiqul Islam, Amin Lutful Kabir, Masuda Begum
Format: Article
Language:English
Published: Bangabandhu Sheikh Mujib Medical University 2016-12-01
Series:Bangabandhu Sheikh Mujib Medical University Journal
Subjects:
Online Access:https://www.banglajol.info/index.php/BSMMUJ/article/view/29939
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spelling doaj-772945aa9ebb4fbc91eaf85d4a68790e2020-11-25T01:04:35ZengBangabandhu Sheikh Mujib Medical UniversityBangabandhu Sheikh Mujib Medical University Journal2074-29082224-77502016-12-019410.3329/bsmmuj.v9i4.2993919590Arthritis as a presentation of acute leukemiaMd. Abdul Aziz0Surozit Kumar Sarkar1Farzana Rahman2Shafiqul Islam3Amin Lutful Kabir4Masuda Begum5Department of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Kazi Nazrul Islam Avenue, Shahbag, DhakaDepartment of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Kazi Nazrul Islam Avenue, Shahbag, DhakaDepartment of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Kazi Nazrul Islam Avenue, Shahbag, DhakaDepartment of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Kazi Nazrul Islam Avenue, Shahbag, DhakaDepartment of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Kazi Nazrul Islam Avenue, Shahbag, DhakaDepartment of Hematology, Faculty of Medicine, Bangabandhu Sheikh Mujib Medical University, Kazi Nazrul Islam Avenue, Shahbag, Dhaka A 14 year old boy presented with 3 months history of low back pain as well as pain and swelling of both knee joints. The pain was inflammatory in nature. He was thoroughly evaluated but no underlying cause was detected. However, the boy was treated with NSAIDs and sulphasalazine. A few weeks later he developed anemia and took the blood transfusion. Then he developed fever and the joint pain re-appeared. On examination, the patient was found moderately anemic, positive bony tenderness and splenomegaly. Musculoskeletal examination revealed right knee joint effusion. The investigation revealed pancytopenia. Bone marrow morphology and immunophenotyping revealed acute lymphoblastic leukemia. We treated the patient according to modified UKALL-2003 protocol and patient condition improved and arthritis disappeared. https://www.banglajol.info/index.php/BSMMUJ/article/view/29939ArthritisLeukemia
collection DOAJ
language English
format Article
sources DOAJ
author Md. Abdul Aziz
Surozit Kumar Sarkar
Farzana Rahman
Shafiqul Islam
Amin Lutful Kabir
Masuda Begum
spellingShingle Md. Abdul Aziz
Surozit Kumar Sarkar
Farzana Rahman
Shafiqul Islam
Amin Lutful Kabir
Masuda Begum
Arthritis as a presentation of acute leukemia
Bangabandhu Sheikh Mujib Medical University Journal
Arthritis
Leukemia
author_facet Md. Abdul Aziz
Surozit Kumar Sarkar
Farzana Rahman
Shafiqul Islam
Amin Lutful Kabir
Masuda Begum
author_sort Md. Abdul Aziz
title Arthritis as a presentation of acute leukemia
title_short Arthritis as a presentation of acute leukemia
title_full Arthritis as a presentation of acute leukemia
title_fullStr Arthritis as a presentation of acute leukemia
title_full_unstemmed Arthritis as a presentation of acute leukemia
title_sort arthritis as a presentation of acute leukemia
publisher Bangabandhu Sheikh Mujib Medical University
series Bangabandhu Sheikh Mujib Medical University Journal
issn 2074-2908
2224-7750
publishDate 2016-12-01
description A 14 year old boy presented with 3 months history of low back pain as well as pain and swelling of both knee joints. The pain was inflammatory in nature. He was thoroughly evaluated but no underlying cause was detected. However, the boy was treated with NSAIDs and sulphasalazine. A few weeks later he developed anemia and took the blood transfusion. Then he developed fever and the joint pain re-appeared. On examination, the patient was found moderately anemic, positive bony tenderness and splenomegaly. Musculoskeletal examination revealed right knee joint effusion. The investigation revealed pancytopenia. Bone marrow morphology and immunophenotyping revealed acute lymphoblastic leukemia. We treated the patient according to modified UKALL-2003 protocol and patient condition improved and arthritis disappeared.
topic Arthritis
Leukemia
url https://www.banglajol.info/index.php/BSMMUJ/article/view/29939
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AT farzanarahman arthritisasapresentationofacuteleukemia
AT shafiqulislam arthritisasapresentationofacuteleukemia
AT aminlutfulkabir arthritisasapresentationofacuteleukemia
AT masudabegum arthritisasapresentationofacuteleukemia
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