Glycyrrhizic Acid Can Attenuate Metabolic Deviations Caused by a High-Sucrose Diet without Causing Water Retention in Male Sprague-Dawley Rats

Glycyrrhizic Acid Can Attenuate Metabolic Deviations Caused by a High-Sucrose Diet without Causing Water Retention in Male Sprague-Dawley Rats

Glycyrrhizic acid (GA) ameliorates many components of the metabolic syndrome, but its potential therapeutic use is marred by edema caused by inhibition of renal 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2). We assessed whether 100 mg/kg per day GA administered orally could promote metabolic benefit...

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Bibliographic Details
Main Authors: Hamish Alexander Fernando, Chanchal Chandramouli, Dayang Rosli, Yi Lyn Lam, Sheau Ting Yong, Hui Ping Yaw, So Ha Ton, Khalid Abdul Kadir, Amanda Sainsbury
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Nutrients
Subjects:
glycyrrhizic acid
metabolic syndrome
high-sucrose diet
11β-HSD2
side effects
edema
angiotensin II
electrolytes
Online Access:http://www.mdpi.com/2072-6643/6/11/4856

Internet

http://www.mdpi.com/2072-6643/6/11/4856

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