THE GC-MS DETERMINATION OF CHEMICAL CONSTITUENTS FROM HARPAGOPHYTUM PROCUMBENS DC ROOTS
<p>The present work is devoted to the study of the component composition of the volatile fraction of the heptanoic extract from <em>Harpagophytum procumbens</em> roots (“Starwest Botanicals”, USA).</p><p>For this purpose the use of gas chromatography-mass spectrometry (...
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doaj-77443aef45ad4555812082c7b249ee1c2020-11-25T03:46:36ZengScientific Route OÜTechnology Transfer: Innovative Solutions in Medicine2585-66262585-66342017-10-0100525410.21303/2585-663.2017.00449385THE GC-MS DETERMINATION OF CHEMICAL CONSTITUENTS FROM HARPAGOPHYTUM PROCUMBENS DC ROOTSAnna Kriukova0Inna Vladimirova1National Universiry of Pharmacy 53, Pushkinska str. Kharkiv, 61002, UkraineNational University of Pharmacy 53, Pushkinska str. Kharkiv, 61002, Ukraine<p>The present work is devoted to the study of the component composition of the volatile fraction of the heptanoic extract from <em>Harpagophytum procumbens</em> roots (“Starwest Botanicals”, USA).</p><p>For this purpose the use of gas chromatography-mass spectrometry (GC-MS) was proposed. The GC-MS analysis was carried out on an Agilent 6890N/5973 inert gas chromatograph/ mass selective detector (Agilent Technologies, USA).</p><p>The quantitative content of the components was calculated by the method of the internal standard. The components with the probability of coincidence for mass spectra of more than 90% were taken into account.</p><p>As a result of the study more than 31 substances have been identified. Among the main groups of compounds the presence of aromatic hydrocarbons, esters and fatty acids, as well as alkanes and alkenes should be mentioned. Hexadecanoic acid (29.92 mg/kg), Octadec-9-enoic acid (21.39 mg/kg), 8-[4-[N-Aziridyl]butyl]amino-2,6-dimethyl-2,6-octadiene (6.46 mg/kg), Pentacosane (5.85 mg/kg), Hexadecanoic acid, trimethylsilyl ester (4.53 mg/kg) prevail in terms of quantity.</p>Based on the results obtained the conclusion can be made that <em>Harpagophytum procumbens</em> DC is a promising herbal source for obtaining active ingredients with the anti-inflammatory, regenerative, analgesic, immunostimulating propertieshttp://eu-jr.eu/ttism/article/view/449harpagophytum procumbens dcchemical constituentschemical structuregas chromatography combined with mass spectrometry |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anna Kriukova Inna Vladimirova |
spellingShingle |
Anna Kriukova Inna Vladimirova THE GC-MS DETERMINATION OF CHEMICAL CONSTITUENTS FROM HARPAGOPHYTUM PROCUMBENS DC ROOTS Technology Transfer: Innovative Solutions in Medicine harpagophytum procumbens dc chemical constituents chemical structure gas chromatography combined with mass spectrometry |
author_facet |
Anna Kriukova Inna Vladimirova |
author_sort |
Anna Kriukova |
title |
THE GC-MS DETERMINATION OF CHEMICAL CONSTITUENTS FROM HARPAGOPHYTUM PROCUMBENS DC ROOTS |
title_short |
THE GC-MS DETERMINATION OF CHEMICAL CONSTITUENTS FROM HARPAGOPHYTUM PROCUMBENS DC ROOTS |
title_full |
THE GC-MS DETERMINATION OF CHEMICAL CONSTITUENTS FROM HARPAGOPHYTUM PROCUMBENS DC ROOTS |
title_fullStr |
THE GC-MS DETERMINATION OF CHEMICAL CONSTITUENTS FROM HARPAGOPHYTUM PROCUMBENS DC ROOTS |
title_full_unstemmed |
THE GC-MS DETERMINATION OF CHEMICAL CONSTITUENTS FROM HARPAGOPHYTUM PROCUMBENS DC ROOTS |
title_sort |
gc-ms determination of chemical constituents from harpagophytum procumbens dc roots |
publisher |
Scientific Route OÜ |
series |
Technology Transfer: Innovative Solutions in Medicine |
issn |
2585-6626 2585-6634 |
publishDate |
2017-10-01 |
description |
<p>The present work is devoted to the study of the component composition of the volatile fraction of the heptanoic extract from <em>Harpagophytum procumbens</em> roots (“Starwest Botanicals”, USA).</p><p>For this purpose the use of gas chromatography-mass spectrometry (GC-MS) was proposed. The GC-MS analysis was carried out on an Agilent 6890N/5973 inert gas chromatograph/ mass selective detector (Agilent Technologies, USA).</p><p>The quantitative content of the components was calculated by the method of the internal standard. The components with the probability of coincidence for mass spectra of more than 90% were taken into account.</p><p>As a result of the study more than 31 substances have been identified. Among the main groups of compounds the presence of aromatic hydrocarbons, esters and fatty acids, as well as alkanes and alkenes should be mentioned. Hexadecanoic acid (29.92 mg/kg), Octadec-9-enoic acid (21.39 mg/kg), 8-[4-[N-Aziridyl]butyl]amino-2,6-dimethyl-2,6-octadiene (6.46 mg/kg), Pentacosane (5.85 mg/kg), Hexadecanoic acid, trimethylsilyl ester (4.53 mg/kg) prevail in terms of quantity.</p>Based on the results obtained the conclusion can be made that <em>Harpagophytum procumbens</em> DC is a promising herbal source for obtaining active ingredients with the anti-inflammatory, regenerative, analgesic, immunostimulating properties |
topic |
harpagophytum procumbens dc chemical constituents chemical structure gas chromatography combined with mass spectrometry |
url |
http://eu-jr.eu/ttism/article/view/449 |
work_keys_str_mv |
AT annakriukova thegcmsdeterminationofchemicalconstituentsfromharpagophytumprocumbensdcroots AT innavladimirova thegcmsdeterminationofchemicalconstituentsfromharpagophytumprocumbensdcroots AT annakriukova gcmsdeterminationofchemicalconstituentsfromharpagophytumprocumbensdcroots AT innavladimirova gcmsdeterminationofchemicalconstituentsfromharpagophytumprocumbensdcroots |
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1724505417076178944 |