Stage 1 Registered Report: Variation in neurodevelopmental outcomes in children with sex chromosome trisomies: protocol for a test of the double hit hypothesis [version 1; referees: 1 approved, 2 approved with reservations]
Background: The presence of an extra sex chromosome is associated with an increased rate of neurodevelopmental difficulties involving language. Group averages, however, obscure a wide range of outcomes. Hypothesis: The 'double hit' hypothesis proposes that the adverse impact of the extra s...
Main Authors: | Dianne F. Newbury, Nuala H. Simpson, Paul A. Thompson, Dorothy V. M. Bishop |
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Format: | Article |
Language: | English |
Published: |
Wellcome
2018-02-01
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Series: | Wellcome Open Research |
Online Access: | https://wellcomeopenresearch.org/articles/3-10/v1 |
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