Noninvasive evaluation of the barrier properties of the skin
Skin as an organ of protection covers the body and accomplishes multiple defensive functions. The intact skin represents a barrier to the uncontrolled loss of water, proteins, and plasma components from the organism. Due to its complex structure, the epidermal barrier with its major component, strat...
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Saratov State Medical University
2014-09-01
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Online Access: | http://www.ssmj.ru/system/files/2014_03-01_512-517.pdf |
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doaj-7774b21d927246f69eeceba73729d1ee2021-07-02T09:40:56ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал2076-25182014-09-011035125173797Noninvasive evaluation of the barrier properties of the skin Utz S.R.0Karakaeva A.V.1Galkina E.M.2Saratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversitySkin as an organ of protection covers the body and accomplishes multiple defensive functions. The intact skin represents a barrier to the uncontrolled loss of water, proteins, and plasma components from the organism. Due to its complex structure, the epidermal barrier with its major component, stratum corneum, is the rate-limiting unit for the penetration of exogenous substances through the skin. The epidermal barrier is not a static structure. The permeability barrier status can be modified by different external and internal factors such as climate, physical stressors, and a number of skin and systemic diseases. Today, different non-invasive approaches are used to monitor the skin barrier physical properties in vivo. The quantification of parameters such as transepidermal water loss, stratum corneum hydration, and skin surface acidity is essential for the integral evaluation of the epidermal barrier status. This paper will allow the readership to get acquainted with the non-invasive, in vivo methods for the investigation of the skin barrier.http://www.ssmj.ru/system/files/2014_03-01_512-517.pdfepidermal barriernon-invasive diagnostic methodstransepidermal water loss |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
Utz S.R. Karakaeva A.V. Galkina E.M. |
spellingShingle |
Utz S.R. Karakaeva A.V. Galkina E.M. Noninvasive evaluation of the barrier properties of the skin Саратовский научно-медицинский журнал epidermal barrier non-invasive diagnostic methods transepidermal water loss |
author_facet |
Utz S.R. Karakaeva A.V. Galkina E.M. |
author_sort |
Utz S.R. |
title |
Noninvasive evaluation of the barrier properties of the skin |
title_short |
Noninvasive evaluation of the barrier properties of the skin |
title_full |
Noninvasive evaluation of the barrier properties of the skin |
title_fullStr |
Noninvasive evaluation of the barrier properties of the skin |
title_full_unstemmed |
Noninvasive evaluation of the barrier properties of the skin |
title_sort |
noninvasive evaluation of the barrier properties of the skin |
publisher |
Saratov State Medical University |
series |
Саратовский научно-медицинский журнал |
issn |
2076-2518 |
publishDate |
2014-09-01 |
description |
Skin as an organ of protection covers the body and accomplishes multiple defensive functions. The intact skin represents a barrier to the uncontrolled loss of water, proteins, and plasma components from the organism. Due to its complex structure, the epidermal barrier with its major component, stratum corneum, is the rate-limiting unit for the penetration of exogenous substances through the skin. The epidermal barrier is not a static structure. The permeability barrier status can be modified by different external and internal factors such as climate, physical stressors, and a number of skin and systemic diseases. Today, different non-invasive approaches are used to monitor the skin barrier physical properties in vivo. The quantification of parameters such as transepidermal water loss, stratum corneum hydration, and skin surface acidity is essential for the integral evaluation of the epidermal barrier status. This paper will allow the readership to get acquainted with the non-invasive, in vivo methods for the investigation of the skin barrier. |
topic |
epidermal barrier non-invasive diagnostic methods transepidermal water loss |
url |
http://www.ssmj.ru/system/files/2014_03-01_512-517.pdf |
work_keys_str_mv |
AT utzsr noninvasiveevaluationofthebarrierpropertiesoftheskin AT karakaevaav noninvasiveevaluationofthebarrierpropertiesoftheskin AT galkinaem noninvasiveevaluationofthebarrierpropertiesoftheskin |
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