Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA.
Cell migration is of paramount importance to organism development and maintenance as well as multiple pathological processes, including cancer metastasis. The RhoGTPases Rac1 and RhoA are indispensable for cell migration as they regulate cell protrusion, cell-extracellular matrix (ECM) interactions...
Main Authors: | Nicholas O Deakin, Christoph Ballestrem, Christopher E Turner |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3358283?pdf=render |
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