RNA-Based CTC Analysis Provides Prognostic Information in Metastatic Breast Cancer

RNA-Based CTC Analysis Provides Prognostic Information in Metastatic Breast Cancer

In metastatic breast cancer (MBC) the molecular characterization of circulating tumor cells (CTCs) provides a unique tool to understand metastasis-biology and therapy-resistance. We evaluated the prognostic significance of gene expression in EpCAM<sup>(+)</sup> CTCs in 46 MBC patients ba...

Full description

Bibliographic Details
Main Authors:	Areti Strati, Michail Nikolaou, Vassilis Georgoulias, Evi S. Lianidou
Format:	Article
Language:	English
Published:	MDPI AG 2021-03-01
Series:	Diagnostics
Subjects:	liquid biopsy circulating tumor cells gene expression metastatic breast cancer multiplex RT-qPCR prognostic marker
Online Access:	https://www.mdpi.com/2075-4418/11/3/513

Similar Items

Prognostic Significance of <i>TWIST1</i>, <i>CD24</i>, <i>CD44</i>, and <i>ALDH1</i> Transcript Quantification in EpCAM-Positive Circulating Tumor Cells from Early Stage Breast Cancer Patients
by: Areti Strati, et al.
Published: (2019-06-01)

<i>PIM-1</i> Is Overexpressed at a High Frequency in Circulating Tumor Cells from Metastatic Castration-Resistant Prostate Cancer Patients
by: Athina Markou, et al.
Published: (2020-05-01)

A Comparison of Three Methods for the Detection of Circulating Tumor Cells in Patients with Early and Metastatic Breast Cancer
by: Eleni Politaki, et al.
Published: (2017-11-01)

Evaluation of Monocarboxylate Transporter 4 (MCT4) Expression and Its Prognostic Significance in Circulating Tumor Cells From Patients With Early Stage Non-Small-Cell Lung Cancer
by: Athina Markou, et al.
Published: (2021-04-01)

Multicenter Evaluation of Independent High-Throughput and RT-qPCR Technologies for the Development of Analytical Workflows for Circulating miRNA Analysis
by: Anna Babayan, et al.
Published: (2020-05-01)

Natriuretic Peptide Expression and Function in GH3 Somatolactotropes and Feline Somatotrope Pituitary Tumours
by: Samantha M. Mirczuk, et al.
Published: (2021-01-01)

A Microchip for Integrated Single-Cell Gene Expression Profiling and Genotoxicity Detection
by: Hui Dong, et al.
Published: (2016-09-01)

Molekularbiologische Diagnostik von Pflanzenkrankkeiten
by: Grausgruber-Gröger, Sabine, et al.
Published: (2014-09-01)

Validação e uso de transcrição reversa seguida da reação em cadeia pela polimerase em tempo real (RT-qPCR) para a vigilância e diagnóstico de flavivírus transmitidos por mosquitos circulantes no Brasil
by: Mariana Sequetin Cunha
Published: (2018)

Validação e uso de transcrição reversa seguida da reação em cadeia pela polimerase em tempo real (RT-qPCR) para a vigilância e diagnóstico de flavivírus transmitidos por mosquitos circulantes no Brasil
by: Cunha, Mariana Sequetin
Published: (2018)

Molecular Subtype Conversion between Primary and Metastatic Breast Cancer Corresponding to the Dynamics of Apoptotic and Intact Circulating Tumor Cells
by: Stefan Stefanovic, et al.
Published: (2019-03-01)

Simultaneous Detection of Bluetongue Virus Serotypes Using xMAP Technology
by: Martin Ashby, et al.
Published: (2020-10-01)

Cell-Free DNA Variant Sequencing Using CTC-Depleted Blood for Comprehensive Liquid Biopsy Testing in Metastatic Breast Cancer
by: Corinna Keup, et al.
Published: (2019-02-01)

Assessment of the Efficacy and Clinical Utility of Different Circulating Tumor Cell (CTC) Detection Assays in Patients with Chemotherapy-Naïve Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
by: Maria A. Papadaki, et al.
Published: (2021-01-01)

Impact of mRNA-Assessed Molecular Subtype Conversion, Intact and Apoptotic Circulating Tumor Cells on Survival of Metastatic Breast Cancer Patients: Proof of Principle
by: Stefan Stefanovic, et al.
Published: (2020-06-01)

Stumbling on elusive cargo: how isomiRs challenge microRNA detection and quantification, the case of extracellular vesicles
by: S. Eréndira Avendaño-Vázquez, et al.
Published: (2020-01-01)

Prognostic value of CIP2A gene expression in adult Egyptian acute myeloid leukemia patients
by: Roxan E. Shafik, et al.
Published: (2020-08-01)

Detection of EGFR Mutations in Plasma cfDNA and Paired CTCs of NSCLC Patients before and after Osimertinib Therapy Using Crystal Digital PCR
by: Aliki Ntzifa, et al.
Published: (2021-05-01)

Heterogeneous expression of EPCAM in human circulating tumour cells from patient-derived xenografts
by: Chiara Agnoletto, et al.
Published: (2018-10-01)

Longitudinal Analysis of Circulating Tumor Cells in Colorectal Cancer Patients by a Cytological and Molecular Approach: Feasibility and Clinical Application
by: Alexander Hendricks, et al.
Published: (2021-06-01)

Quantitative PCR Measurement of miR-371a-3p and miR-372-p Is Influenced by Hemolysis
by: Mette Pernille Myklebust, et al.
Published: (2019-05-01)

Sampling, Logistics, and Analytics of Urine for RT-qPCR-based Diagnostics
by: Rosel Kretschmer-Kazemi Far, et al.
Published: (2021-08-01)

Prognostic and clinicopathological significance of circulating tumor cells detected by RT-PCR in non-metastatic colorectal cancer: a meta-analysis and systematic review
by: Chaogang Yang, et al.
Published: (2017-11-01)

A Novel Multiplex qRT-PCR Assay to Detect SARS-CoV-2 Infection: High Sensitivity and Increased Testing Capacity
by: Sara Petrillo, et al.
Published: (2020-07-01)

Eradication of Measurable Residual Disease in AML: A Challenging Clinical Goal
by: Paolo Bernasconi, et al.
Published: (2021-06-01)

Human Sapovirus among Outpatients with Acute Gastroenteritis in Spain: A One-Year Study
by: Miguel F. Varela, et al.
Published: (2019-02-01)

Rapid RNA analysis of individual Caenorhabditis elegans
by: Kien Ly, et al.
Published: (2015-01-01)

Molecular detection of human astrovirus in an urban sewage treatment plant in Rio de Janeiro, Brazil
by: Flávia Ramos Guimarães, et al.
Published: (2008-12-01)

Analysis of <it>ZAP70</it> expression in adult acute lymphoblastic leukaemia by real time quantitative PCR
by: Chakupurakal Geothy, et al.
Published: (2012-05-01)

Transcriptome Profiling of Louisiana iris Root and Identification of Genes Involved in Lead-Stress Response
by: Songqing Tian, et al.
Published: (2015-11-01)

Diagnostic Leukapheresis Enables Reliable Transcriptomic Profiling of Single Circulating Tumor Cells to Characterize Inter-Cellular Heterogeneity in Terms of Endocrine Resistance
by: Florian Reinhardt, et al.
Published: (2019-06-01)

Population Analysis and Subgroup Diagnosis of Lettuce necrotic yellows virus in New Zealand
by: Darling, Toni Louise
Published: (2021)

Identificação in silico e perfil transcricional de genes candidatos a efetores de Austropuccinia psidii
by: Lopes, Mariana da Silva
Published: (2017)

Prognostic Significance of Gene Expression and DNA Methylation Markers in Circulating Tumor Cells and Paired Plasma Derived Exosomes in Metastatic Castration Resistant Prostate Cancer
by: Martha Zavridou, et al.
Published: (2021-02-01)

Diagnostic accuracy of LAMP versus PCR over the course of SARS-CoV-2 infection
by: Masato Inaba, et al.
Published: (2021-06-01)

Evaluation of RT-qPCR and Loop-Mediated Isothermal Amplification (LAMP) Assays for the Detection of SARS-CoV-2 in Argentina
by: María Dolores Fellner, et al.
Published: (2021-04-01)

Diagnostic Value of Circulating miR-202 in Early-Stage Breast Cancer in South Korea
by: Jungho Kim, et al.
Published: (2020-07-01)

Baseline Splenic Volume as a Prognostic Biomarker of FOLFIRI Efficacy and a Surrogate Marker of MDSC Accumulation in Metastatic Colorectal Carcinoma
by: Julie Niogret, et al.
Published: (2020-05-01)

Comparison of Two MicroRNA Quantification Methods for Assaying MicroRNA Expression Profiles in Wheat (Triticum aestivum L.)
by: Ran HAN, et al.
Published: (2014-04-01)

PROGNOSTIC FACTORS FOR SURVIVAL IN PATIENTS WITH METASTATIC COLORECTAL CANCER TREATED WITH FIRST - LINE CHEMOTHERAPY
by: Deyan Davidov
Published: (2017-05-01)

Cannot write session to /tmp/vufind_sessions/sess_be8phaer75d693dfp9ck8h6jf9