Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs

Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs

Nipah virus (NiV) is an emergent pathogen capable of causing acute respiratory illness and fatal encephalitis in pigs and humans. A high fatality rate and broad host tropism makes NiV a serious public and animal health concern. There is therefore an urgent need for a NiV vaccines to protect animals...

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Bibliographic Details
Main Authors: Miriam Pedrera, Francesca Macchi, Rebecca K. McLean, Valentina Franceschi, Nazia Thakur, Luca Russo, Lobna Medfai, Shawn Todd, Elma Z. Tchilian, Jean-Christophe Audonnet, Keith Chappell, Ariel Isaacs, Daniel Watterson, Paul R. Young, Glenn A. Marsh, Dalan Bailey, Simon P. Graham, Gaetano Donofrio
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Vaccines
Subjects:
nipah virus
bovine herpes virus 4
vaccine
pig
immunogenicity
Online Access:https://www.mdpi.com/2076-393X/8/1/115

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