Oleanolic acid initiates apoptosis in non-small cell lung cancer cell lines and reduces metastasis of a B16F10 melanoma model in vivo.
<h4>Background</h4>Drug resistance, a process mediated by multiple mechanisms, is a critical determinant for treating lung cancer. The aim of this study is to determine if oleanolic acid (OA), a pentacyclic triterpene present in several plants, is able to circumvent the mechanisms of dru...
Main Authors: | Kelly Araújo Lúcio, Gleice da Graça Rocha, Leonardo Campos Monção-Ribeiro, Janaina Fernandes, Christina Maeda Takiya, Cerli Rocha Gattass |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22174843/pdf/?tool=EBI |
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