Unexpected Formation of 4-aryl-1-(Propane-2-ylidenehydrazono)-2,3-diazaspiro[5.5]undec-3-ene by the Reaction of Pyridazinethiones Derivatives with Hydrazine
After making a new series of spiro[cycloalkane]pyridazinones with high Fsp<sup>3</sup> character available, the new target was to synthesize derivatives comprising nitrogen-containing heterocycles, such as triazolo or tetrazolo rings. The corresponding thioxo derivatives (<b>1a<...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
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Series: | Molbank |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-8599/2021/3/M1243 |
Summary: | After making a new series of spiro[cycloalkane]pyridazinones with high Fsp<sup>3</sup> character available, the new target was to synthesize derivatives comprising nitrogen-containing heterocycles, such as triazolo or tetrazolo rings. The corresponding thioxo derivatives (<b>1a</b>,<b>b</b>) seemed to be good starting materials for the synthesis of tetrazolo derivatives. The reaction of the pyridazinethiones (<b>1a,b</b>) with hydrazine surprisingly resulted in Schiff bases (<b>3a</b>,<b>b</b>) deriving from the reaction of hydrazones (<b>2a</b>,<b>b</b>) with acetone. |
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ISSN: | 1422-8599 |