Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis.

Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis.

Adipose-derived stem cells (ASCs) exhibit self-renewal and pluripotency. The differentiation potency of ASCs has been reported to deteriorate with aging; however, relevant studies used ASCs that were isolated and subcultured several times. It is still unclear whether subcultured ASCs accurately refl...

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Bibliographic Details
Main Authors: Yuta Doshida, Haruka Sano, Sadahiro Iwabuchi, Toshiro Aigaki, Masayuki Yoshida, Shinichi Hashimoto, Akihito Ishigami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242171

Internet

https://doi.org/10.1371/journal.pone.0242171

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