Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report

<p>Abstract</p> <p>Introduction</p> <p>Invasive pulmonary aspergillosis is a leading cause of mortality and morbidity in bone marrow transplant recipients. Establishing the diagnosis remains a challenge for clinicians working in acute care setting. However, prompt diagn...

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Main Authors: Rashid Rifat, Denning David W
Format: Article
Language:English
Published: BMC 2009-01-01
Series:Journal of Medical Case Reports
Online Access:http://www.jmedicalcasereports.com/content/3/1/26
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spelling doaj-77e36d56a48943008a2b5a93843d15212020-11-25T00:20:37ZengBMCJournal of Medical Case Reports1752-19472009-01-01312610.1186/1752-1947-3-26Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case reportRashid RifatDenning David W<p>Abstract</p> <p>Introduction</p> <p>Invasive pulmonary aspergillosis is a leading cause of mortality and morbidity in bone marrow transplant recipients. Establishing the diagnosis remains a challenge for clinicians working in acute care setting. However, prompt diagnosis and treatment can lead to favourable outcomes</p> <p>Case presentation</p> <p>We report a case of invasive aspergillosis occurring in a 39-year-old Caucasian female 10 years after an allogeneic haematopoietic bone marrow transplant, and 5 years after stopping all immunosuppression. Possible risk factors include bronchiolitis obliterans and exposure to building dust (for example, handling her husband's dusty overalls). There are no similar case reports in the literature at this time.</p> <p>Conclusion</p> <p>High clinical suspicion, especially in the setting of failure to respond to broad-spectrum antibiotics, should alert clinicians to the possibility of invasive pulmonary aspergillosis, which, in this case, responded to antifungal therapy.</p> http://www.jmedicalcasereports.com/content/3/1/26
collection DOAJ
language English
format Article
sources DOAJ
author Rashid Rifat
Denning David W
spellingShingle Rashid Rifat
Denning David W
Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report
Journal of Medical Case Reports
author_facet Rashid Rifat
Denning David W
author_sort Rashid Rifat
title Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report
title_short Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report
title_full Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report
title_fullStr Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report
title_full_unstemmed Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report
title_sort invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report
publisher BMC
series Journal of Medical Case Reports
issn 1752-1947
publishDate 2009-01-01
description <p>Abstract</p> <p>Introduction</p> <p>Invasive pulmonary aspergillosis is a leading cause of mortality and morbidity in bone marrow transplant recipients. Establishing the diagnosis remains a challenge for clinicians working in acute care setting. However, prompt diagnosis and treatment can lead to favourable outcomes</p> <p>Case presentation</p> <p>We report a case of invasive aspergillosis occurring in a 39-year-old Caucasian female 10 years after an allogeneic haematopoietic bone marrow transplant, and 5 years after stopping all immunosuppression. Possible risk factors include bronchiolitis obliterans and exposure to building dust (for example, handling her husband's dusty overalls). There are no similar case reports in the literature at this time.</p> <p>Conclusion</p> <p>High clinical suspicion, especially in the setting of failure to respond to broad-spectrum antibiotics, should alert clinicians to the possibility of invasive pulmonary aspergillosis, which, in this case, responded to antifungal therapy.</p>
url http://www.jmedicalcasereports.com/content/3/1/26
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