Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report
<p>Abstract</p> <p>Introduction</p> <p>Invasive pulmonary aspergillosis is a leading cause of mortality and morbidity in bone marrow transplant recipients. Establishing the diagnosis remains a challenge for clinicians working in acute care setting. However, prompt diagn...
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doaj-77e36d56a48943008a2b5a93843d15212020-11-25T00:20:37ZengBMCJournal of Medical Case Reports1752-19472009-01-01312610.1186/1752-1947-3-26Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case reportRashid RifatDenning David W<p>Abstract</p> <p>Introduction</p> <p>Invasive pulmonary aspergillosis is a leading cause of mortality and morbidity in bone marrow transplant recipients. Establishing the diagnosis remains a challenge for clinicians working in acute care setting. However, prompt diagnosis and treatment can lead to favourable outcomes</p> <p>Case presentation</p> <p>We report a case of invasive aspergillosis occurring in a 39-year-old Caucasian female 10 years after an allogeneic haematopoietic bone marrow transplant, and 5 years after stopping all immunosuppression. Possible risk factors include bronchiolitis obliterans and exposure to building dust (for example, handling her husband's dusty overalls). There are no similar case reports in the literature at this time.</p> <p>Conclusion</p> <p>High clinical suspicion, especially in the setting of failure to respond to broad-spectrum antibiotics, should alert clinicians to the possibility of invasive pulmonary aspergillosis, which, in this case, responded to antifungal therapy.</p> http://www.jmedicalcasereports.com/content/3/1/26 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rashid Rifat Denning David W |
spellingShingle |
Rashid Rifat Denning David W Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report Journal of Medical Case Reports |
author_facet |
Rashid Rifat Denning David W |
author_sort |
Rashid Rifat |
title |
Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report |
title_short |
Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report |
title_full |
Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report |
title_fullStr |
Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report |
title_full_unstemmed |
Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report |
title_sort |
invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report |
publisher |
BMC |
series |
Journal of Medical Case Reports |
issn |
1752-1947 |
publishDate |
2009-01-01 |
description |
<p>Abstract</p> <p>Introduction</p> <p>Invasive pulmonary aspergillosis is a leading cause of mortality and morbidity in bone marrow transplant recipients. Establishing the diagnosis remains a challenge for clinicians working in acute care setting. However, prompt diagnosis and treatment can lead to favourable outcomes</p> <p>Case presentation</p> <p>We report a case of invasive aspergillosis occurring in a 39-year-old Caucasian female 10 years after an allogeneic haematopoietic bone marrow transplant, and 5 years after stopping all immunosuppression. Possible risk factors include bronchiolitis obliterans and exposure to building dust (for example, handling her husband's dusty overalls). There are no similar case reports in the literature at this time.</p> <p>Conclusion</p> <p>High clinical suspicion, especially in the setting of failure to respond to broad-spectrum antibiotics, should alert clinicians to the possibility of invasive pulmonary aspergillosis, which, in this case, responded to antifungal therapy.</p> |
url |
http://www.jmedicalcasereports.com/content/3/1/26 |
work_keys_str_mv |
AT rashidrifat invasivepulmonaryaspergillosis10yearspostbonemarrowtransplantationacasereport AT denningdavidw invasivepulmonaryaspergillosis10yearspostbonemarrowtransplantationacasereport |
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