β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistance.
Beta-catenin plays an important role in embryogenesis and carcinogenesis by controlling either cadherin-mediated cell adhesion or transcriptional activation of target gene expression. In many types of cancers nuclear translocation of beta-catenin has been observed. Our data indicate that during mela...
Main Authors: | Tobias Sinnberg, Moritz Menzel, Daniel Ewerth, Birgit Sauer, Michael Schwarz, Martin Schaller, Claus Garbe, Birgit Schittek |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3157382?pdf=render |
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