Effects of chronic stress on the onset and progression of Huntington's disease in transgenic mice
Huntington's disease (HD) is a neurodegenerative disease caused by a tandem repeat mutation encoding an expanded polyglutamine tract. Our previous work showed that memory deficits in HD transgenic mice could be accelerated by increased levels of stress hormone, while memory in WT mice remained...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-11-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996114002022 |