Characterization of human cancer xenografts in humanized mice

BackgroundPreclinical evaluation of drugs targeting the human immune system has posed challenges for oncology researchers. Since the commercial introduction of humanized mice, antitumor efficacy and pharmacodynamic studies can now be performed with human cancer cells within mice bearing components o...

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Bibliographic Details
Main Authors: Jonathan Rios-Doria, Christina Stevens, Christopher Maddage, Kerri Lasky
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000416.full