Assembly and Function of Gonad-Specific Non-Membranous Organelles in <i>Drosophila</i> piRNA Biogenesis

Assembly and Function of Gonad-Specific Non-Membranous Organelles in <i>Drosophila</i> piRNA Biogenesis

PIWI-interacting RNAs (piRNAs) are small non-coding RNAs that repress transposons in animal germlines. This protects the genome from the invasive DNA elements. piRNA pathway failures lead to DNA damage, gonadal development defects, and infertility. Thus, the piRNA pathway is indispensable for the co...

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Bibliographic Details
Main Authors: Shigeki Hirakata, Mikiko C. Siomi
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Non-Coding RNA
Subjects:
piwi
pirna
transposon
yb body
flam body
dot com
nuage
mitochondrion
<i>drosophila</i>
ovary
Online Access:https://www.mdpi.com/2311-553X/5/4/52

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