Research progress of scaffolds for promoting the vascularization of regenerated dental pulp
Endothelial regeneration is a research hotspot in the field of dental pulp. The regeneration of endodontic blood flow is the bottleneck of dental pulp regeneration, and the applied scaffold material is the key to revascularization. Stent materials were reviewed. The literature review Results show th...
Main Authors: | , |
---|---|
Format: | Article |
Language: | zho |
Published: |
Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
2020-03-01
|
Series: | 口腔疾病防治 |
Subjects: | |
Online Access: | http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2020.03.012 |
id |
doaj-785a52f2744d4e0bbf136f401b3020f6 |
---|---|
record_format |
Article |
spelling |
doaj-785a52f2744d4e0bbf136f401b3020f62020-11-25T02:40:14ZzhoEditorial Department of Journal of Prevention and Treatment for Stomatological Diseases口腔疾病防治2096-14562096-14562020-03-0128320020410.12016/j.issn.2096-1456.2020.03.012Research progress of scaffolds for promoting the vascularization of regenerated dental pulpLIU Huimin0LI Xiangwei1Department of Conservative Dentistry and Endodontics, School and Hospital of Stomatology, Jilin UniversityDepartment of Conservative Dentistry and Endodontics, School and Hospital of Stomatology, Jilin UniversityEndothelial regeneration is a research hotspot in the field of dental pulp. The regeneration of endodontic blood flow is the bottleneck of dental pulp regeneration, and the applied scaffold material is the key to revascularization. Stent materials were reviewed. The literature review Results show that, depending on the source of the stent material used for endodontic revascularization, there are mainly natural, synthetic and composite materials. The natural scaffold materials used for vascular regeneration include chitosan, hyaluronic acid, bacterial cellulose, and proanthocyanidin; artificial scaffold materials include hydrogel, cryogel, and electrospinning. The bionic composite scaffold system with a double-layer tubular structure is low immunogenicity and good biocompatibility. Studies on the scaffold materials of bionic extracellular matrix, such as injectable hydrogels/microspheres, have promoted the development of dental pulp regeneration, that is, uniformly distributed scaffold materials in the root canal promote the generation of pulp-like tissue; Whether dental pulp tissue can establish effective blood circulation through the apical foramen remains a great challenge.http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2020.03.012dental pulp vasculardental pulp regenerationvascularizationtissue engineeringscaffold materialchitosaninjectable hydrogels/microspheresbiomimetic scaffolds |
collection |
DOAJ |
language |
zho |
format |
Article |
sources |
DOAJ |
author |
LIU Huimin LI Xiangwei |
spellingShingle |
LIU Huimin LI Xiangwei Research progress of scaffolds for promoting the vascularization of regenerated dental pulp 口腔疾病防治 dental pulp vascular dental pulp regeneration vascularization tissue engineering scaffold material chitosan injectable hydrogels/microspheres biomimetic scaffolds |
author_facet |
LIU Huimin LI Xiangwei |
author_sort |
LIU Huimin |
title |
Research progress of scaffolds for promoting the vascularization of regenerated dental pulp |
title_short |
Research progress of scaffolds for promoting the vascularization of regenerated dental pulp |
title_full |
Research progress of scaffolds for promoting the vascularization of regenerated dental pulp |
title_fullStr |
Research progress of scaffolds for promoting the vascularization of regenerated dental pulp |
title_full_unstemmed |
Research progress of scaffolds for promoting the vascularization of regenerated dental pulp |
title_sort |
research progress of scaffolds for promoting the vascularization of regenerated dental pulp |
publisher |
Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases |
series |
口腔疾病防治 |
issn |
2096-1456 2096-1456 |
publishDate |
2020-03-01 |
description |
Endothelial regeneration is a research hotspot in the field of dental pulp. The regeneration of endodontic blood flow is the bottleneck of dental pulp regeneration, and the applied scaffold material is the key to revascularization. Stent materials were reviewed. The literature review Results show that, depending on the source of the stent material used for endodontic revascularization, there are mainly natural, synthetic and composite materials. The natural scaffold materials used for vascular regeneration include chitosan, hyaluronic acid, bacterial cellulose, and proanthocyanidin; artificial scaffold materials include hydrogel, cryogel, and electrospinning. The bionic composite scaffold system with a double-layer tubular structure is low immunogenicity and good biocompatibility. Studies on the scaffold materials of bionic extracellular matrix, such as injectable hydrogels/microspheres, have promoted the development of dental pulp regeneration, that is, uniformly distributed scaffold materials in the root canal promote the generation of pulp-like tissue; Whether dental pulp tissue can establish effective blood circulation through the apical foramen remains a great challenge. |
topic |
dental pulp vascular dental pulp regeneration vascularization tissue engineering scaffold material chitosan injectable hydrogels/microspheres biomimetic scaffolds |
url |
http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2020.03.012 |
work_keys_str_mv |
AT liuhuimin researchprogressofscaffoldsforpromotingthevascularizationofregenerateddentalpulp AT lixiangwei researchprogressofscaffoldsforpromotingthevascularizationofregenerateddentalpulp |
_version_ |
1724782293935980544 |