Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in Taiwan
Essential tremor (ET) is a common neurological disorder and the most common movement disorder. Low-level occupational exposure to mercury vapor is known to be a crucial factor that increases the risk of tremor. Dental amalgam is one of the main sources of mercury in those who possess amalgam restora...
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doaj-7879b111416a45c8abf2d7a46328e79e2020-11-25T02:38:54ZengMDPI AGInternational Journal of Environmental Research and Public Health1660-46012020-01-0117378010.3390/ijerph17030780ijerph17030780Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in TaiwanChien-Fang Tseng0Kun-Huang Chen1Hui-Chieh Yu2Yu-Chao Chang3School of Dentistry, Chung Shan Medical University, Taichung 40201, TaiwanDepartment of Artificial Intelligence, CTBC Business School, Tainan 709, TaiwanSchool of Dentistry, Chung Shan Medical University, Taichung 40201, TaiwanSchool of Dentistry, Chung Shan Medical University, Taichung 40201, TaiwanEssential tremor (ET) is a common neurological disorder and the most common movement disorder. Low-level occupational exposure to mercury vapor is known to be a crucial factor that increases the risk of tremor. Dental amalgam is one of the main sources of mercury in those who possess amalgam restorations. However, the relationship between ET and amalgam filling (AMF) is not quite clear. The purpose of this study was to investigate the association between AMF and the risk of ET using a population-based administrative databank. The data for this study were sourced from the Taiwanese National Health Insurance Research Database (NHIRD). A retrospective case-control study was conducted using this databank from 2000 to 2013. Case and control groups were matched by sex, age, urbanization level, monthly income, and Charlson comorbidity index using the propensity score method with a 1:1 ratio. In this study, 3008 cases and 3008 controls were included. The results from this nationwide population-based case-control study did not indicate any association between ET and AMF in Taiwan. Although the results were not significantly statistical, the findings may be worthy to be valued.https://www.mdpi.com/1660-4601/17/3/780essential tremordental amalgam fillingsnationwide populationcase-control study |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chien-Fang Tseng Kun-Huang Chen Hui-Chieh Yu Yu-Chao Chang |
spellingShingle |
Chien-Fang Tseng Kun-Huang Chen Hui-Chieh Yu Yu-Chao Chang Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in Taiwan International Journal of Environmental Research and Public Health essential tremor dental amalgam fillings nationwide population case-control study |
author_facet |
Chien-Fang Tseng Kun-Huang Chen Hui-Chieh Yu Yu-Chao Chang |
author_sort |
Chien-Fang Tseng |
title |
Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in Taiwan |
title_short |
Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in Taiwan |
title_full |
Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in Taiwan |
title_fullStr |
Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in Taiwan |
title_full_unstemmed |
Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in Taiwan |
title_sort |
association between dental amalgam filling and essential tremor: a nationwide population-based case control study in taiwan |
publisher |
MDPI AG |
series |
International Journal of Environmental Research and Public Health |
issn |
1660-4601 |
publishDate |
2020-01-01 |
description |
Essential tremor (ET) is a common neurological disorder and the most common movement disorder. Low-level occupational exposure to mercury vapor is known to be a crucial factor that increases the risk of tremor. Dental amalgam is one of the main sources of mercury in those who possess amalgam restorations. However, the relationship between ET and amalgam filling (AMF) is not quite clear. The purpose of this study was to investigate the association between AMF and the risk of ET using a population-based administrative databank. The data for this study were sourced from the Taiwanese National Health Insurance Research Database (NHIRD). A retrospective case-control study was conducted using this databank from 2000 to 2013. Case and control groups were matched by sex, age, urbanization level, monthly income, and Charlson comorbidity index using the propensity score method with a 1:1 ratio. In this study, 3008 cases and 3008 controls were included. The results from this nationwide population-based case-control study did not indicate any association between ET and AMF in Taiwan. Although the results were not significantly statistical, the findings may be worthy to be valued. |
topic |
essential tremor dental amalgam fillings nationwide population case-control study |
url |
https://www.mdpi.com/1660-4601/17/3/780 |
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