Analysis of elimination half-lives in MamTKDB 1.0 related to bioaccumulation: Requirement of repeated administration and blood plasma values underrepresent tissues
When building the novel public mammalian toxicokinetic database (MamTKDB) we collected and included 3927 elimination half-lives (elimt1/2) for 1407 xenobiotics in various species (rat, human, mouse, dog, monkey, rabbit, cattle, pig, sheep, guinea pig, hamster, horse and goat) with specification of c...
Main Authors: | Tim Hofer, Oddvar Myhre, Johanna Peltola-Thies, Doris Hirmann |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-10-01
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Series: | Environment International |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412021002178 |
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