Generation of a human Neurochondrin deficient iPSC line KICRi002-A-3 using CRISPR/Cas9

The role of Neurochondrin (NCDN) in humans is not well understood. Mice with a conditional Ncdn knock-out show epileptic seizures, depressive-like behaviours and impaired spatial learning. Using CRISPR/Cas9, we generated a Neurochondrin deficient human iPSC line KICRi002-A-3 carrying a homozygous 75...

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Bibliographic Details
Main Authors: Ambrin Fatima, Jens Schuster, Talia Akram, Maria Sobol, Jan Hoeber, Niklas Dahl
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120300623

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