Iron status in small for gestational age and appropriate for gestational age infants at birth
Purpose This study compared the iron statuses of small for gestational age (SGA) and appropriate for gestational age (AGA) infants at birth. Methods The clinical data of 904 newborn infants admitted to the neonatal intensive care unit were reviewed. Blood samples were drawn from the infants within 2...
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doaj-78954ea9482a49b6aa747d1dbdbcdf872020-11-25T01:11:30ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582019-03-0162310210710.3345/kjp.2018.0665320125553492Iron status in small for gestational age and appropriate for gestational age infants at birthHyeon A Kim0Sook-Hyun Park1Eun Joo Lee Department of Pediatrics, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea Department of Pediatrics, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, KoreaPurpose This study compared the iron statuses of small for gestational age (SGA) and appropriate for gestational age (AGA) infants at birth. Methods The clinical data of 904 newborn infants admitted to the neonatal intensive care unit were reviewed. Blood samples were drawn from the infants within 24 hours after birth. Serum ferritin level was used as a marker of total iron status. Results In this study, 115 SGA (GA, 36.5±2.9 weeks; birth weight [BW], 1,975±594.5 g) and 717 AGA (GA, 35.1±3.5 weeks; BW, 2,420.3±768.7 g) infants were included. The SGA infants had higher hematocrit levels (50.6%±5.8% vs. 47.7%±5.7%, P<0.05) than the AGA infants. No difference in serum ferritin level (ng/mL) was found between the groups (mean [95% confidence interval]: SGA vs. AGA infants, 139.0 [70.0–237.0] vs. 141.0 [82.5–228.5]). After adjusting for gestational age, the SGA infants had lower ferritin levels (147.1 ng/mL [116.3–178.0 ng/mL] vs. 189.4 ng/mL [178.0–200.8 ng/ mL], P<0.05). Total body iron stores were also lower in the SGA infants than in the AGA infants (185.6 [153.4–211.7] vs 202.2 [168.7–241.9], P<0.05). Conclusion The SGA infants had lower ferritin and total body iron stores than the AGA infants. The SGA infants affected by maternal hypertension who were born at late preterm had an additional risk of inadequate iron store. Iron deficiency should be monitored in these infants during follow-up.http://kjp.or.kr/upload/pdf/kjp-2018-06653.pdfIron storesSmall for gestational ageNeonate |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hyeon A Kim Sook-Hyun Park Eun Joo Lee |
spellingShingle |
Hyeon A Kim Sook-Hyun Park Eun Joo Lee Iron status in small for gestational age and appropriate for gestational age infants at birth Korean Journal of Pediatrics Iron stores Small for gestational age Neonate |
author_facet |
Hyeon A Kim Sook-Hyun Park Eun Joo Lee |
author_sort |
Hyeon A Kim |
title |
Iron status in small for gestational age and appropriate for gestational age infants at birth |
title_short |
Iron status in small for gestational age and appropriate for gestational age infants at birth |
title_full |
Iron status in small for gestational age and appropriate for gestational age infants at birth |
title_fullStr |
Iron status in small for gestational age and appropriate for gestational age infants at birth |
title_full_unstemmed |
Iron status in small for gestational age and appropriate for gestational age infants at birth |
title_sort |
iron status in small for gestational age and appropriate for gestational age infants at birth |
publisher |
Korean Pediatric Society |
series |
Korean Journal of Pediatrics |
issn |
1738-1061 2092-7258 |
publishDate |
2019-03-01 |
description |
Purpose This study compared the iron statuses of small for gestational age (SGA) and appropriate for gestational age (AGA) infants at birth. Methods The clinical data of 904 newborn infants admitted to the neonatal intensive care unit were reviewed. Blood samples were drawn from the infants within 24 hours after birth. Serum ferritin level was used as a marker of total iron status. Results In this study, 115 SGA (GA, 36.5±2.9 weeks; birth weight [BW], 1,975±594.5 g) and 717 AGA (GA, 35.1±3.5 weeks; BW, 2,420.3±768.7 g) infants were included. The SGA infants had higher hematocrit levels (50.6%±5.8% vs. 47.7%±5.7%, P<0.05) than the AGA infants. No difference in serum ferritin level (ng/mL) was found between the groups (mean [95% confidence interval]: SGA vs. AGA infants, 139.0 [70.0–237.0] vs. 141.0 [82.5–228.5]). After adjusting for gestational age, the SGA infants had lower ferritin levels (147.1 ng/mL [116.3–178.0 ng/mL] vs. 189.4 ng/mL [178.0–200.8 ng/ mL], P<0.05). Total body iron stores were also lower in the SGA infants than in the AGA infants (185.6 [153.4–211.7] vs 202.2 [168.7–241.9], P<0.05). Conclusion The SGA infants had lower ferritin and total body iron stores than the AGA infants. The SGA infants affected by maternal hypertension who were born at late preterm had an additional risk of inadequate iron store. Iron deficiency should be monitored in these infants during follow-up. |
topic |
Iron stores Small for gestational age Neonate |
url |
http://kjp.or.kr/upload/pdf/kjp-2018-06653.pdf |
work_keys_str_mv |
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