Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models

An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on...

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Bibliographic Details
Main Authors: Marco D’Andrea, Marcello Benassi, Lidia Strigari
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2016/2796186
Description
Summary:An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points.
ISSN:1748-670X
1748-6718