Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models

Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models

An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on...

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Bibliographic Details
Main Authors: Marco D’Andrea, Marcello Benassi, Lidia Strigari
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2016/2796186
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spelling doaj-7896ad67a8724b88b61f6705daa8ff752020-11-24T22:40:05ZengHindawi LimitedComputational and Mathematical Methods in Medicine1748-670X1748-67182016-01-01201610.1155/2016/27961862796186Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological ModelsMarco D’Andrea0Marcello Benassi1Lidia Strigari2Laboratory of Medical Physics and Expert Systems, Regina Elena National Cancer Institute, Rome, ItalyLaboratory of Medical Physics and Expert Systems, Regina Elena National Cancer Institute, Rome, ItalyLaboratory of Medical Physics and Expert Systems, Regina Elena National Cancer Institute, Rome, ItalyAn overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points.http://dx.doi.org/10.1155/2016/2796186
collection DOAJ
language English
format Article
sources DOAJ
author Marco D’Andrea
Marcello Benassi
Lidia Strigari
spellingShingle Marco D’Andrea
Marcello Benassi
Lidia Strigari
Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
Computational and Mathematical Methods in Medicine
author_facet Marco D’Andrea
Marcello Benassi
Lidia Strigari
author_sort Marco D’Andrea
title Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title_short Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title_full Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title_fullStr Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title_full_unstemmed Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title_sort modeling radiotherapy induced normal tissue complications: an overview beyond phenomenological models
publisher Hindawi Limited
series Computational and Mathematical Methods in Medicine
issn 1748-670X
1748-6718
publishDate 2016-01-01
description An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points.
url http://dx.doi.org/10.1155/2016/2796186
work_keys_str_mv AT marcodandrea modelingradiotherapyinducednormaltissuecomplicationsanoverviewbeyondphenomenologicalmodels
AT marcellobenassi modelingradiotherapyinducednormaltissuecomplicationsanoverviewbeyondphenomenologicalmodels
AT lidiastrigari modelingradiotherapyinducednormaltissuecomplicationsanoverviewbeyondphenomenologicalmodels
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