Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals
Equid herpesvirus type 1 is primarily a respiratory tract virus associated with poor athletic performance that can also cause late gestation abortion, neonatal foal death and encephalomyelopathy. Horizontal transmission is well described, whereas evidence of vertical transmission of equid herpesviru...
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doaj-7896c90d2fb54d44b2aa54f9eb54d07c2020-11-25T00:41:59ZengAOSISJournal of the South African Veterinary Association1019-91282224-94352019-05-01900e1e510.4102/jsava.v90i0.17361333Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foalsLara J. Brown0Geoff Brown1Julia Kydd2Tom A.E. Stout3Martin L. Schulman4Department of Production Animal Studies, University of Pretoria, PretoriaSection of Reproduction, Department of Production Animal Studies, University of Pretoria, PretoriaSchool of Veterinary Medicine and Science, University of Nottingham, LeicestershireDepartment of Production Animal Studies, University of Pretoria, Pretoria, South Africa; and, Department of Equine Sciences, Utrecht University, Utrecht, NetherlandsDepartment of Production Animal Studies, University of Pretoria, PretoriaEquid herpesvirus type 1 is primarily a respiratory tract virus associated with poor athletic performance that can also cause late gestation abortion, neonatal foal death and encephalomyelopathy. Horizontal transmission is well described, whereas evidence of vertical transmission of equid herpesvirus type 1 associated with the birth of a healthy foal has not been demonstrated. This study sampled a population of Thoroughbred mares (n = 71), and their healthy neonatal foals and foetal membranes, to test for the presence of both equid herpesvirus types 1 and 4 using a quantitative polymerase chain reaction assay. Foetal membrane swabs and tissue samples were taken immediately post-partum, and venous blood samples and nasal swabs were obtained from both mare and foal 8 h after birth. Neither equid herpesvirus type 1 nor equid herpesvirus type 4 nucleic acid was detected in any sample, and it was concluded that there was no active shedding of equid herpesvirus types 1 and 4 at the time of sampling. Consequently, no evidence of vertical transmission of these viruses could be found on this stud farm during the sampling period.https://jsava.co.za/index.php/jsava/article/view/1736equinesequid herpesvirus type 1 and 4placentaefoetal membranesfoalsqPCRlatencyThoroughbred |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lara J. Brown Geoff Brown Julia Kydd Tom A.E. Stout Martin L. Schulman |
spellingShingle |
Lara J. Brown Geoff Brown Julia Kydd Tom A.E. Stout Martin L. Schulman Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals Journal of the South African Veterinary Association equines equid herpesvirus type 1 and 4 placentae foetal membranes foals qPCR latency Thoroughbred |
author_facet |
Lara J. Brown Geoff Brown Julia Kydd Tom A.E. Stout Martin L. Schulman |
author_sort |
Lara J. Brown |
title |
Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals |
title_short |
Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals |
title_full |
Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals |
title_fullStr |
Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals |
title_full_unstemmed |
Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals |
title_sort |
failure to detect equid herpesvirus types 1 and 4 dna in placentae and healthy new-born thoroughbred foals |
publisher |
AOSIS |
series |
Journal of the South African Veterinary Association |
issn |
1019-9128 2224-9435 |
publishDate |
2019-05-01 |
description |
Equid herpesvirus type 1 is primarily a respiratory tract virus associated with poor athletic performance that can also cause late gestation abortion, neonatal foal death and encephalomyelopathy. Horizontal transmission is well described, whereas evidence of vertical transmission of equid herpesvirus type 1 associated with the birth of a healthy foal has not been demonstrated. This study sampled a population of Thoroughbred mares (n = 71), and their healthy neonatal foals and foetal membranes, to test for the presence of both equid herpesvirus types 1 and 4 using a quantitative polymerase chain reaction assay. Foetal membrane swabs and tissue samples were taken immediately post-partum, and venous blood samples and nasal swabs were obtained from both mare and foal 8 h after birth. Neither equid herpesvirus type 1 nor equid herpesvirus type 4 nucleic acid was detected in any sample, and it was concluded that there was no active shedding of equid herpesvirus types 1 and 4 at the time of sampling. Consequently, no evidence of vertical transmission of these viruses could be found on this stud farm during the sampling period. |
topic |
equines equid herpesvirus type 1 and 4 placentae foetal membranes foals qPCR latency Thoroughbred |
url |
https://jsava.co.za/index.php/jsava/article/view/1736 |
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