Microbiological and Antimicrobial Profile of Pathogens Associated with Pediatric Urinary Tract Infection: A One Year Retrospective Study from A Tertiary Care Teaching Hospita
Introduction: Urinary tract infections in the pediatric population are second only to respiratory tract infections. There is limited information on bacterial resistance to commonly used antibiotics or on the risk factors for increased resistance in these patients. Settings and Design: A retrosp...
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doaj-78a208b5ad11434aa99c3fd1f18abf0b2020-11-25T01:44:23ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822014-03-01314710.7860/NJLM/2014/7651:2001Microbiological and Antimicrobial Profile of Pathogens Associated with Pediatric Urinary Tract Infection: A One Year Retrospective Study from A Tertiary Care Teaching HospitaSavitha Nagaraj 0 Bhuvanesh Sukhlal Kalal 1Nivedita Kamath2Sethumadhavan Muralidharan3Associate Professor, Department of Microbiology, St. John’s Medical College, Bangalore, IndiaResearch Assistant, Department of Microbiology, St. John’s Medical College, Bangalore, India.Assistant Professor, Department of Pediatrics, St. John’s Medical College, Bangalore, India.Professor and Head, Department of Microbiology, St. John’s Medical College, Bangalore, India.Introduction: Urinary tract infections in the pediatric population are second only to respiratory tract infections. There is limited information on bacterial resistance to commonly used antibiotics or on the risk factors for increased resistance in these patients. Settings and Design: A retrospective study was carried out to evaluate the microbiological and antimicrobial profile of uropathogens isolated in between January 2011 and December 2011 from the pediatrics department, St John’s Medical College Hospital, a tertiary-care setting in Bangalore, India. Materials and Methods: Urine samples were collected by the mid-stream “clean catch” method and were tested microbiologically by standard procedures. Antibiotic susceptibility of the isolated pathogens was tested for commonly-used antibiotics by Kirby-Bauer technique according to CLIS guidelines. Results: Of 1254 samples tested, 357 (28.5%) showed significant growth and 229 (64.3%) were from children less than 5 years of age, more commonly in males. Escherichia coli (54.4%) was the leading uropathogen, resistant to cephalosporin (78%), fluroquinolones (76.8%) and sensitive to aminoglycoside antibiotics (72.6%). Klebsiella spp. was found to be highly resistant to many of the antimicrobials as compared to other gram negative bacilli. The incidence of Candida spp. was higher in pediatric intensive care unit (39%). Pediatric surgery unit had higher rates of isolation (42.7%) and Pseudomonas spp., NFGNB and Enterococcus spp. were common. Conclusion: High level of antimicrobial resistance amongst the pathogens causing urinary tract infection observed in pediatric population. http://www.njlm.net/articles/PDF/2001/2-%207651_CE(Ra)_F(P)_PF1(Pr_P)_PFA(H)_OLF.pdfantibiotic susceptibilitychildrenuropathogens |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Savitha Nagaraj Bhuvanesh Sukhlal Kalal Nivedita Kamath Sethumadhavan Muralidharan |
spellingShingle |
Savitha Nagaraj Bhuvanesh Sukhlal Kalal Nivedita Kamath Sethumadhavan Muralidharan Microbiological and Antimicrobial Profile of Pathogens Associated with Pediatric Urinary Tract Infection: A One Year Retrospective Study from A Tertiary Care Teaching Hospita National Journal of Laboratory Medicine antibiotic susceptibility children uropathogens |
author_facet |
Savitha Nagaraj Bhuvanesh Sukhlal Kalal Nivedita Kamath Sethumadhavan Muralidharan |
author_sort |
Savitha Nagaraj |
title |
Microbiological and Antimicrobial Profile of Pathogens Associated with Pediatric Urinary Tract Infection: A One Year Retrospective Study from A Tertiary Care Teaching Hospita |
title_short |
Microbiological and Antimicrobial Profile of Pathogens Associated with Pediatric Urinary Tract Infection: A One Year Retrospective Study from A Tertiary Care Teaching Hospita |
title_full |
Microbiological and Antimicrobial Profile of Pathogens Associated with Pediatric Urinary Tract Infection: A One Year Retrospective Study from A Tertiary Care Teaching Hospita |
title_fullStr |
Microbiological and Antimicrobial Profile of Pathogens Associated with Pediatric Urinary Tract Infection: A One Year Retrospective Study from A Tertiary Care Teaching Hospita |
title_full_unstemmed |
Microbiological and Antimicrobial Profile of Pathogens Associated with Pediatric Urinary Tract Infection: A One Year Retrospective Study from A Tertiary Care Teaching Hospita |
title_sort |
microbiological and antimicrobial profile of pathogens associated with pediatric urinary tract infection: a one year retrospective study from a tertiary care teaching hospita |
publisher |
JCDR Research and Publications Pvt. Ltd. |
series |
National Journal of Laboratory Medicine |
issn |
2277-8551 2455-6882 |
publishDate |
2014-03-01 |
description |
Introduction: Urinary tract infections in the pediatric
population are second only to respiratory tract infections.
There is limited information on bacterial resistance to
commonly used antibiotics or on the risk factors for
increased resistance in these patients.
Settings and Design: A retrospective study was carried out
to evaluate the microbiological and antimicrobial profile of
uropathogens isolated in between January 2011 and December
2011 from the pediatrics department, St John’s Medical College
Hospital, a tertiary-care setting in Bangalore, India.
Materials and Methods: Urine samples were collected
by the mid-stream “clean catch” method and were tested
microbiologically by standard procedures. Antibiotic
susceptibility of the isolated pathogens was tested for
commonly-used antibiotics by Kirby-Bauer technique
according to CLIS guidelines.
Results: Of 1254 samples tested, 357 (28.5%) showed
significant growth and 229 (64.3%) were from children less
than 5 years of age, more commonly in males. Escherichia
coli (54.4%) was the leading uropathogen, resistant
to cephalosporin (78%), fluroquinolones (76.8%) and
sensitive to aminoglycoside antibiotics (72.6%). Klebsiella
spp. was found to be highly resistant to many of the
antimicrobials as compared to other gram negative bacilli.
The incidence of Candida spp. was higher in pediatric
intensive care unit (39%). Pediatric surgery unit had higher
rates of isolation (42.7%) and Pseudomonas spp., NFGNB
and Enterococcus spp. were common.
Conclusion: High level of antimicrobial resistance amongst
the pathogens causing urinary tract infection observed in
pediatric population.
|
topic |
antibiotic susceptibility children uropathogens |
url |
http://www.njlm.net/articles/PDF/2001/2-%207651_CE(Ra)_F(P)_PF1(Pr_P)_PFA(H)_OLF.pdf |
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