Summary: | Loss of the modulatory role of the endothelium may
be an important factor in the development of diabetic
vascular diseases such as cardiac, cerebral and
peripheral vascular disease, as evidenced by changes
in the serum lipid profile: increased triglycerides
(TG), total lipoprotein cholesterol (TC) and lowdensity
lipoprotein (LDL-C), and reduced highdensity
lipoprotein (HDL-C). This article describes a
longitudinal intervention study conducted at the Center
for Research in Diabetes and Endocrinometabolic
Diseases of the Federal University of Ceará (UFC, CE,
Brazil), in which 58 patients with type 2 diabetes (DM2)
were monitored by recording biochemical parameters
during two sessions of laboratory tests, and through
monthly interview-based pharmacotherapeutic followup.
The study lasted one year and was approved by the
human research ethics committee of UFC. The data
collected were analyzed with the aid of the program
SPSS 11.0. Hypertension was present in 54.4% of
patients with DM2, 64% were sedentary and overweight,
44.7% reported having relatives with cardiovascular
disease and 59.5% had a family history of diabetes. The
serum levels of fasting glucose, TG, TC and LDL-C and
the systolic and diastolic blood pressure were reduced
after the active follow-up and monitoring of patients.
This result reinforces the importance of the role of the
pharmacist in the control of biochemical parameters,
improvement of patients’ quality of life and prevention
of complications.
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