Antimicrobial efficacy of commercially available mouthrinses: An in vitro study
Introduction: Oral cavity ecosystem represents a dynamic pattern. An effective plaque control measure should target plaque formation before the mature plaque is formed. Various types of chemotherapeutic agents are coming up with different antimicrobial agents in them. Hence, this study has been unde...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2016-01-01
|
Series: | Journal of Indian Association of Public Health Dentistry |
Subjects: | |
Online Access: | http://www.jiaphd.org/article.asp?issn=2319-5932;year=2016;volume=14;issue=4;spage=463;epage=468;aulast=Mruthyuenjaya |
id |
doaj-78c74dda4d0841768c9ffe4064393c72 |
---|---|
record_format |
Article |
spelling |
doaj-78c74dda4d0841768c9ffe4064393c722020-11-25T01:24:12ZengWolters Kluwer Medknow PublicationsJournal of Indian Association of Public Health Dentistry2319-59322350-04842016-01-0114446346810.4103/2319-5932.195841Antimicrobial efficacy of commercially available mouthrinses: An in vitro studyRoopavathi Kallahalli MruthyuenjayaSanjay VenugopalChikkanayakanahalli Parashuramayya SateeshDarshana BennadiB V RenushreeIntroduction: Oral cavity ecosystem represents a dynamic pattern. An effective plaque control measure should target plaque formation before the mature plaque is formed. Various types of chemotherapeutic agents are coming up with different antimicrobial agents in them. Hence, this study has been undertaken to know whether these antimicrobial agents are effective on common microorganisms of oral cavity which directly and indirectly contributes to plaque formation Aim: The aim of this study was to determine antimicrobial efficacy of different mouthrinses against the oral pathogens in vitro. Materials and Methods: A total of seven mouthrinses were tested for their antimicrobial activity against three oral pathogens, namely, Streptococcus mutans (MTCC 890), Escherichia coli (ATCC 25922), and Candida albicans (ATCC 10231) by well agar diffusion assay. Statistical analysis was performed using Kruskal–Wallis test. The level of significance used was P< 0.05. Results: Mouthrinse with chlorhexidine (CHX) gluconate, triclosan as main ingredients showed maximum zone of inhibition (P = 0.003) against streptococcal mutans and E. coli at 1:16 dilution and mouthrinse with CHX gluconate and zinc chloride showed maximum zone of inhibition at 1:16 dilution against Candida among seven mouthrinses used in the present study. It was also observed that zone of inhibition of all the mouthrinses decreased with the increase in dilution. Conclusion: Among mouthrinses formulations, CHX combined with other active ingredients was found to be more effective.http://www.jiaphd.org/article.asp?issn=2319-5932;year=2016;volume=14;issue=4;spage=463;epage=468;aulast=MruthyuenjayaAntimicrobial activityantimicrobial agentschlorhexidine gluconatemouthrinse |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Roopavathi Kallahalli Mruthyuenjaya Sanjay Venugopal Chikkanayakanahalli Parashuramayya Sateesh Darshana Bennadi B V Renushree |
spellingShingle |
Roopavathi Kallahalli Mruthyuenjaya Sanjay Venugopal Chikkanayakanahalli Parashuramayya Sateesh Darshana Bennadi B V Renushree Antimicrobial efficacy of commercially available mouthrinses: An in vitro study Journal of Indian Association of Public Health Dentistry Antimicrobial activity antimicrobial agents chlorhexidine gluconate mouthrinse |
author_facet |
Roopavathi Kallahalli Mruthyuenjaya Sanjay Venugopal Chikkanayakanahalli Parashuramayya Sateesh Darshana Bennadi B V Renushree |
author_sort |
Roopavathi Kallahalli Mruthyuenjaya |
title |
Antimicrobial efficacy of commercially available mouthrinses: An in vitro study |
title_short |
Antimicrobial efficacy of commercially available mouthrinses: An in vitro study |
title_full |
Antimicrobial efficacy of commercially available mouthrinses: An in vitro study |
title_fullStr |
Antimicrobial efficacy of commercially available mouthrinses: An in vitro study |
title_full_unstemmed |
Antimicrobial efficacy of commercially available mouthrinses: An in vitro study |
title_sort |
antimicrobial efficacy of commercially available mouthrinses: an in vitro study |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Indian Association of Public Health Dentistry |
issn |
2319-5932 2350-0484 |
publishDate |
2016-01-01 |
description |
Introduction: Oral cavity ecosystem represents a dynamic pattern. An effective plaque control measure should target plaque formation before the mature plaque is formed. Various types of chemotherapeutic agents are coming up with different antimicrobial agents in them. Hence, this study has been undertaken to know whether these antimicrobial agents are effective on common microorganisms of oral cavity which directly and indirectly contributes to plaque formation Aim: The aim of this study was to determine antimicrobial efficacy of different mouthrinses against the oral pathogens in vitro. Materials and Methods: A total of seven mouthrinses were tested for their antimicrobial activity against three oral pathogens, namely, Streptococcus mutans (MTCC 890), Escherichia coli (ATCC 25922), and Candida albicans (ATCC 10231) by well agar diffusion assay. Statistical analysis was performed using Kruskal–Wallis test. The level of significance used was P< 0.05. Results: Mouthrinse with chlorhexidine (CHX) gluconate, triclosan as main ingredients showed maximum zone of inhibition (P = 0.003) against streptococcal mutans and E. coli at 1:16 dilution and mouthrinse with CHX gluconate and zinc chloride showed maximum zone of inhibition at 1:16 dilution against Candida among seven mouthrinses used in the present study. It was also observed that zone of inhibition of all the mouthrinses decreased with the increase in dilution. Conclusion: Among mouthrinses formulations, CHX combined with other active ingredients was found to be more effective. |
topic |
Antimicrobial activity antimicrobial agents chlorhexidine gluconate mouthrinse |
url |
http://www.jiaphd.org/article.asp?issn=2319-5932;year=2016;volume=14;issue=4;spage=463;epage=468;aulast=Mruthyuenjaya |
work_keys_str_mv |
AT roopavathikallahallimruthyuenjaya antimicrobialefficacyofcommerciallyavailablemouthrinsesaninvitrostudy AT sanjayvenugopal antimicrobialefficacyofcommerciallyavailablemouthrinsesaninvitrostudy AT chikkanayakanahalliparashuramayyasateesh antimicrobialefficacyofcommerciallyavailablemouthrinsesaninvitrostudy AT darshanabennadi antimicrobialefficacyofcommerciallyavailablemouthrinsesaninvitrostudy AT bvrenushree antimicrobialefficacyofcommerciallyavailablemouthrinsesaninvitrostudy |
_version_ |
1725118293297070080 |