Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children
Introduction. Obesity is a worldwide concern. It is associated with morbidity such as dyslipidemia and liver disease. Childhood obesity has dramatically increased, particularly in the Gulf region. We aim to assess the prevalence of dyslipidemia and fatty liver disease (FLD) in overweight and obese c...
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doaj-78c90e7d4e6b419d9a245c08992f61e42020-11-24T20:45:16ZengHindawi LimitedJournal of Obesity2090-07082090-07162018-01-01201810.1155/2018/86268188626818Dyslipidemia and Fatty Liver Disease in Overweight and Obese ChildrenAsma Deeb0Salima Attia1Samia Mahmoud2Ghada Elhaj3Abubaker Elfatih4Pediatric Endocrinology Department, Mafraq Hospital, P.O. Box 2951, Abu Dhabi, UAEPediatric Endocrinology Department, Mafraq Hospital, P.O. Box 2951, Abu Dhabi, UAEPediatric Clinic, Police Health Services, Abu Dhabi, UAEPrimary Health Care Center, BaniYas, Abu Dhabi, UAEBiochemistry Department, Shaikh Khalifa Medical City, Abu Dhabi, UAEIntroduction. Obesity is a worldwide concern. It is associated with morbidity such as dyslipidemia and liver disease. Childhood obesity has dramatically increased, particularly in the Gulf region. We aim to assess the prevalence of dyslipidemia and fatty liver disease (FLD) in overweight and obese children and analyze the association between different anthropometric measures with dyslipidemia and fatty liver disease. Methods. A descriptive, cross-sectional study conducted on children referred with obesity. BMI percentiles were plotted and standardized waist circumference (WC) was generated. Family history of metabolic syndrome was recorded. Fasting lipid, liver transaminases, and ultrasound scans (US) for those with elevated enzymes were performed. Descriptive statistics were used for quantitative parameters. Results. 216 participants were recruited. Mean ± SD age was 10.58 ± 2.996 years. 55.3% had dyslipidemia; 11.7% had high cholesterol, 28.6% high triglyceride, 32.7% high LDL, and 18.0% low HDL. 51 (84%) had either elevated transaminases. All had liver US, and 43 had FLD. WC was strongly associated with dyslipidemia and FLD (P=0.04 and 0.003). Conclusion. Dyslipidemia is common in overweight, obese children. FLD is prevalent in those with elevated liver transaminases. WC is an easy tool that can be utilized to screen for dyslipidemia and FLD in overweight and obese children.http://dx.doi.org/10.1155/2018/8626818 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Asma Deeb Salima Attia Samia Mahmoud Ghada Elhaj Abubaker Elfatih |
spellingShingle |
Asma Deeb Salima Attia Samia Mahmoud Ghada Elhaj Abubaker Elfatih Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children Journal of Obesity |
author_facet |
Asma Deeb Salima Attia Samia Mahmoud Ghada Elhaj Abubaker Elfatih |
author_sort |
Asma Deeb |
title |
Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children |
title_short |
Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children |
title_full |
Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children |
title_fullStr |
Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children |
title_full_unstemmed |
Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children |
title_sort |
dyslipidemia and fatty liver disease in overweight and obese children |
publisher |
Hindawi Limited |
series |
Journal of Obesity |
issn |
2090-0708 2090-0716 |
publishDate |
2018-01-01 |
description |
Introduction. Obesity is a worldwide concern. It is associated with morbidity such as dyslipidemia and liver disease. Childhood obesity has dramatically increased, particularly in the Gulf region. We aim to assess the prevalence of dyslipidemia and fatty liver disease (FLD) in overweight and obese children and analyze the association between different anthropometric measures with dyslipidemia and fatty liver disease. Methods. A descriptive, cross-sectional study conducted on children referred with obesity. BMI percentiles were plotted and standardized waist circumference (WC) was generated. Family history of metabolic syndrome was recorded. Fasting lipid, liver transaminases, and ultrasound scans (US) for those with elevated enzymes were performed. Descriptive statistics were used for quantitative parameters. Results. 216 participants were recruited. Mean ± SD age was 10.58 ± 2.996 years. 55.3% had dyslipidemia; 11.7% had high cholesterol, 28.6% high triglyceride, 32.7% high LDL, and 18.0% low HDL. 51 (84%) had either elevated transaminases. All had liver US, and 43 had FLD. WC was strongly associated with dyslipidemia and FLD (P=0.04 and 0.003). Conclusion. Dyslipidemia is common in overweight, obese children. FLD is prevalent in those with elevated liver transaminases. WC is an easy tool that can be utilized to screen for dyslipidemia and FLD in overweight and obese children. |
url |
http://dx.doi.org/10.1155/2018/8626818 |
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