INFLIXIMAB AND TUMOUR NECROSIS FACTOR ALPHA MEASUREMENT ON INTESTINAL MUCOSA: A NEW TOOL FOR THE CLINIC?

INFLIXIMAB AND TUMOUR NECROSIS FACTOR ALPHA MEASUREMENT ON INTESTINAL MUCOSA: A NEW TOOL FOR THE CLINIC?

Background: Infliximab (IFX) trough levels measurement could partially explain mechanisms of loss in response to this drug. However, little information exists on its concentration at the mucosal level or mucosal pharmacokinetics. Objective: The aim of this study was to investigate whether IFX cou...

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Bibliographic Details
Main Authors: Silvia Pecere, Valentina Petito, Arianna Amato, Andrea Poscia, Alessandro Armuzzi, Loris Riccardo Lopetuso, Alessandro Sgambato, Giovanni Cammarota, Alfredo Papa, Antonio Gasbarrini, Franco Scaldaferri
Format: Article
Language:English
Published: European Medical Journal 2016-12-01
Series:European Medical Journal Gastroenterology
Subjects:
inflammatory bowel disease (ibd)
trough levels
infliximab (ifx) mucosal levels
ifx serum levels
tumour necrosis factor alpha (tnf-α)
intestinal mucosa
Online Access:https://www.emjreviews.com/gastroenterology/article/infliximab-and-tumour-necrosis-factor-alpha-measurement-on-intestinal-mucosa-a-new-tool-for-the-clinic/

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